vlcs antibody, fatp2 antibody, vlacs antibody, acsvl1 antibody, facvl1 antibody, im:7139614 antibody, slc27a2 antibody, wu:fb99g05 antibody, zgc:112376 antibody, ACSVL1 antibody, FACVL1 antibody, HsT17226 antibody, hFACVL1 antibody, FATP2 antibody, VLCS antibody, Vlac antibody, Vlacs antibody, VLACS antibody, solute carrier family 27 (fatty acid transporter), member 2 L homeolog antibody, solute carrier family 27 member 2 antibody, solute carrier family 27 (fatty acid transporter), member 2a antibody, solute carrier family 27 (fatty acid transporter), member 2 antibody, slc27a2.L antibody, SLC27A2 antibody, slc27a2a antibody, slc27a2 antibody, Slc27a2 antibody
Background
The protein encoded by this gene is an isozyme of long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme activates long-chain, branched-chain and very-long-chain fatty acids containing 22 or more carbons to their CoA derivatives. It is expressed primarily in liver and kidney, and is present in both endoplasmic reticulum and peroxisomes, but not in mitochondria. Its decreased peroxisomal enzyme activity is in part responsible for the biochemical pathology in X-linked adrenoleukodystrophy. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,SLC27A2,ACSVL1,FACVL1,FATP2,HsT17226,VLACS,VLCS,hFACVL1,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Cardiovascular,Lipids,Fatty Acids,SLC27A2