BRCA1 antibody (pSer1457)
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- Target See all BRCA1 Antibodies
- BRCA1 (Breast Cancer 1 (BRCA1))
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Binding Specificity
- AA 1423-1472, pSer1457
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This BRCA1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Specificity
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BRCA1 (Phospho-Ser1457) Antibody detects endogenous levels of BRCA1 only when phosphorylated at Ser1457.
PhosphorylationH:S1457
- Purification
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
- Purity
- > 95 %
- Immunogen
- The antiserum was produced against synthesized peptide derived from human BRCA1 around the phosphorylation site of Ser1457.
- Isotype
- IgG
- Top Product
- Discover our top product BRCA1 Primary Antibody
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- Application Notes
- WB: 1:500~1:1000 ELISA: 1:1000
- Comment
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Unigene-Number: Hs.194143 (NCBI Gene Symbol: BRCA1)
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Stable at -20°C for at least 1 year.
- Expiry Date
- 12 months
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- Target
- BRCA1 (Breast Cancer 1 (BRCA1))
- Alternative Name
- BRCA1 (BRCA1 Products)
- Synonyms
- BRCAI antibody, BRCC1 antibody, BROVCA1 antibody, IRIS antibody, PNCA4 antibody, PPP1R53 antibody, PSCP antibody, RNF53 antibody, iris antibody, pscp antibody, brcai antibody, brcc1 antibody, rnf53 antibody, brca1 antibody, BRCA1 antibody, LOC100224649 antibody, BRCA1, DNA repair associated antibody, breast cancer 1 antibody, breast cancer 1, early onset antibody, breast cancer 1 L homeolog antibody, BRCA1 antibody, brca1 antibody, LOC755086 antibody, Brca1 antibody, brca1.L antibody
- Background
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Synonyms: BRCA1, Breast cancer type 1 susceptibility protein, familial breast/ovarian cancer gene 1
NCBI Gene Symbol: BRCA1
- Molecular Weight
- 207 kDa
- Gene ID
- 672
- OMIM
- 113705
- UniProt
- P38398
- Pathways
- Cell Division Cycle, DNA Damage Repair, Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Response to DNA Damage Stimulus
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