×
For best experience we recommend to activate Javascript in your browser.
GCLC antibody (AA 286-315)
GCLC
Reactivity: Human, Mouse
WB
Host: Rabbit
Polyclonal
RB37579
unconjugated
Product Details anti-GCLC Antibody
(hide)
Target
See all GCLC Antibodies
GCLC
(Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC))
Binding Specificity
All epitopes for GCLC antibodies
AA 286-315
Reactivity
All reactivities for GCLC antibodies
Human, Mouse
Host
All hosts for GCLC antibodies
Rabbit
Clonality
All clonalities for GCLC antibodies
Polyclonal
Conjugate
All conjugates for GCLC antibodies
This GCLC antibody is un-conjugated
Application
All applications for GCLC antibodies
Western Blotting (WB)
Predicted Reactivity
Rat
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This GCLC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 286-315 amino acids from the Central region of human GCLC.
Clone
RB37579
Isotype
Ig Fraction
Top Product
Discover our top product GCLC Primary Antibody
Alternatives
(show)
anti-Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC) (N-Term) antibody
GCLC
Reactivity: Human, Mouse, Rat, Cow, Zebrafish (Danio rerio), Rabbit, Dog, Guinea Pig, Horse
WB, IHC
Host: Rabbit
Polyclonal
unconjugated
anti-Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC) (Middle Region) antibody
GCLC
Reactivity: Human, Mouse, Rat, Cow, Zebrafish (Danio rerio), Rabbit, Dog, Guinea Pig, Horse, Saccharomyces cerevisiae
WB, IHC
Host: Rabbit
Polyclonal
unconjugated
Application Details
(hide)
Application Notes
WB: 1:1000. WB: 1:1000
Restrictions
For Research Use only
Handling
(hide)
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
GCLC Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
Expiry Date
6 months
Target Details for GCLC
(hide)
Target
GCLC
(Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC))
Alternative Name
GCLC (GCLC Products )
Synonyms
GCLC antibody, gclc antibody, MGC146287 antibody, 2259 antibody, CG2259 antibody, DmGCLC antibody, DmGCS antibody, DmGCSh antibody, Dmel\\CG2259 antibody, GCL antibody, GCLc antibody, GCSh antibody, Gcs antibody, Gcsh antibody, DDBDRAFT_0186120 antibody, DDBDRAFT_0231403 antibody, DDB_0186120 antibody, DDB_0231403 antibody, GCS antibody, GLCL antibody, GLCLC antibody, D9Wsu168e antibody, GLCL-H antibody, Ggcs-hs antibody, Glclc antibody, cb1049 antibody, fe36e11 antibody, wu:fe36e11 antibody, glutamate-cysteine ligase catalytic subunit antibody, glutamate-cysteine ligase, catalytic subunit antibody, Glutamate-cysteine ligase catalytic subunit antibody, gamma glutamylcysteine synthetase antibody, glutamate-cysteine ligase, catalytic subunit L homeolog antibody, glutamate-cysteine ligase, catalytic subunit S homeolog antibody, gamma-glutamylcysteine synthetase antibody, GCLC antibody, gclc antibody, Gclc antibody, LbGCS antibody, gcsA antibody, gclc.L antibody, gclc.S antibody, GSH1 antibody
Background
Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.
Molecular Weight
72766
Gene ID
2729
NCBI Accession
NP_001184044 , NP_001489
UniProt
P48506
Pathways
Cell RedoxHomeostasis
Recently viewed
(hide)