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Cortactin antibody
CTTN
Reactivity: Human
WB
Host: Mouse
Monoclonal
401CT8-6-3
unconjugated
Product Details anti-Cortactin Antibody
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Target
See all Cortactin (CTTN) Antibodies
Cortactin (CTTN)
Reactivity
All reactivities for Cortactin antibodies
Human
Host
All hosts for Cortactin antibodies
Mouse
Clonality
All clonalities for Cortactin antibodies
Monoclonal
Conjugate
All conjugates for Cortactin antibodies
This Cortactin antibody is un-conjugated
Application
All applications for Cortactin antibodies
Western Blotting (WB)
Purification
Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
Immunogen
Purified His-tagged Cortactin protein(Fragment) was used to produced this monoclonal antibody.
Clone
401CT8-6-3
Isotype
IgM
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Alternatives
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Application Details
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Application Notes
WB: 1:1000~8000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Cortactin Antibody(Ascites) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
Expiry Date
6 months
Target Details for Cortactin
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Target
Cortactin (CTTN)
Alternative Name
Cortactin (CTTN Products )
Synonyms
EMS1 antibody, 1110020L01Rik antibody, Ems1 antibody, Cttnb antibody, CG3637 antibody, Dmel\CG3637 antibody, cortactin antibody, cttn antibody, CTTN1 antibody, P85.25 antibody, Cttn antibody, ems1 antibody, CTTN antibody, cortactin antibody, CG3637 gene product from transcript CG3637-RD antibody, cortactin S homeolog antibody, cortactin L homeolog antibody, src substrate cortactin antibody, Src substrate cortactin antibody, CTTN antibody, Cttn antibody, Cortactin antibody, cttn.S antibody, cttn.L antibody, cttn antibody, CpipJ_CPIJ006351 antibody, Bm1_57220 antibody, LOC100533277 antibody
Background
This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.
Molecular Weight
61586
Gene ID
2017
NCBI Accession
NP_001171669 , NP_005222 , NP_612632
UniProt
Q14247
Pathways
MAPK Signaling
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