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Estrogen Receptor alpha antibody (AA 246-273)
ESR1
Reactivity: Human
WB
Host: Mouse
Monoclonal
415CT16-3-2-1
unconjugated
Product Details anti-Estrogen Receptor alpha Antibody
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Target
See all Estrogen Receptor alpha (ESR1) Antibodies
Estrogen Receptor alpha (ESR1)
(Estrogen Receptor 1 (ESR1))
Binding Specificity
All epitopes for Estrogen Receptor alpha antibodies
AA 246-273
Reactivity
All reactivities for Estrogen Receptor alpha antibodies
Human
Host
All hosts for Estrogen Receptor alpha antibodies
Mouse
Clonality
All clonalities for Estrogen Receptor alpha antibodies
Monoclonal
Conjugate
All conjugates for Estrogen Receptor alpha antibodies
This Estrogen Receptor alpha antibody is un-conjugated
Application
All applications for Estrogen Receptor alpha antibodies
Western Blotting (WB)
Predicted Reactivity
B, Hs, M, Pig, Rat
Purification
This antibody is purified through a protein G column, followed by dialysis against PBS.
Immunogen
This ESR1/ER antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 246-273 amino acids from human ESR1/ER.
Clone
415CT16-3-2-1
Isotype
IgG1
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Discover our top product ESR1 Primary Antibody
Alternatives
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Application Details
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Application Notes
WB: 1:100~250
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
ESR1/ER Antibody can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
Expiry Date
6 months
Target Details for Estrogen Receptor alpha
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Target
Estrogen Receptor alpha (ESR1)
(Estrogen Receptor 1 (ESR1))
Alternative Name
ESR1/ER (ESR1 Products )
Synonyms
LOC398734 antibody, AA420328 antibody, AU041214 antibody, ER-alpha antibody, ER[a] antibody, ERa antibody, ERalpha antibody, ESR antibody, Estr antibody, Estra antibody, Nr3a1 antibody, NR3A1 antibody, eralpha antibody, zfER[a] antibody, ER antibody, ESRA antibody, ESTRR antibody, Era antibody, akap12 antibody, cb27 antibody, esr1 antibody, fb72g12 antibody, id:ibd1202 antibody, sb:cb27 antibody, si:ch73-192g21.1 antibody, wu:fb72g12 antibody, wu:fc21c03 antibody, Esr antibody, RNESTROR antibody, ERALPHA antibody, er antibody, esr antibody, nr3a1 antibody, XER antibody, era antibody, esra antibody, ERbeta antibody, xesr-1 antibody, xlERalpha1 antibody, xlERalpha2 antibody, ESR1 antibody, estrogen receptor 1 L homeolog antibody, estrogen receptor 1 (alpha) antibody, estrogen receptor 1 antibody, A kinase (PRKA) anchor protein 12b antibody, esr1.L antibody, Esr1 antibody, ESR1 antibody, esr1 antibody, akap12b antibody
Background
This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.
Molecular Weight
66216
Gene ID
2099
NCBI Accession
NP_000116 , NP_001116212 , NP_001116213 , NP_001116214
UniProt
P03372
Pathways
Nuclear Receptor Transcription Pathway , EGFR Signaling Pathway , Retinoic Acid Receptor Signaling Pathway , Intracellular Steroid Hormone Receptor Signaling Pathway , Steroid Hormone Mediated Signaling Pathway , Ribonucleoprotein Complex Subunit Organization , Ribosome Assembly
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