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Cytochrome C antibody (Cytochrome C, Somatic) (N-Term) Primary Antibody

CYCS Reactivity: Human, Mouse, Rat FACS, WB Host: Rabbit Polyclonal
Pubmed (1)
Catalog No. ABIN1574153
$160.67
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40 μg
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  • Target
    Binding Specificity
    N-Term
    Reactivity
    Human, Mouse, Rat
    Host
    Rabbit
    Clonality
    Polyclonal
    Conjugate
    This Cytochrome C antibody is un-conjugated
    Application
    Flow Cytometry (FACS), Western Blotting (WB)
    Specificity
    Rabbit Anti-Cytochrome C Polyclonal Antibody detects endogenous levels of human and mouse Cytochrome C. Predicted to react with rat Cytochrome C according to sequence homology.
    Cross-Reactivity (Details)
    Rabbit Anti-Cytochrome C Polyclonal Antibody detects endogenous levels of human and mouse Cytochrome C. Predicted to react with rat Cytochrome C according to sequence homology.
    Purification
    Immunoaffinity chromatography.
    Immunogen
    KLH-coupled synthetic peptide from N-terminal of human Cytochrome C .
    Isotype
    IgG
  • Application Notes
    Working concentrations for specific applications should be determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.

    Western blot: 1-2 µg/mLFlow cytometry: 1-3 µg for 1 x 106 cells
    Other applications: user-optimized
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4, containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    Storage
    4 °C/-20 °C
    Storage Comment
    The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.
  • Li, Yu, Gui, Xie, Hong, Zhao, Sheng, Sang, Sun, Wang, Shen, Hong: "Titanium dioxide nanoparticles relieve silk gland damage and increase cocooning of Bombyx mori under phoxim-induced toxicity." in: Journal of agricultural and food chemistry, Vol. 61, Issue 50, pp. 12238-43, 2013 (PubMed).

  • Target
    Alternative Name
    Cytochrome C (CYCS Antibody Abstract)
    Background
    Cytochrome C is an electron transporting protein that resides within the intermembrane space of the mitochondria, where it plays a critical role in the process of oxidative phosphorylation and production of cellular ATP. An increasing amount of interest has been directed toward the role which cytocrome C has been demonstrated to play in apoptotic processes. Following exposure to apoptotic stimuli, cytochrome C is rapidly released from the mitochondria into the cytosol, an event which may be required for the completion of apoptosis in some systems. Cytosolic cytochrome C functions in the activation of caspase 3, an ICE family molecule that is a key effector of apoptosis.Rabbit Anti-Cytochrome C Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide from N-terminal of human Cytochrome C (Swiss Prot: P99999).
    Pathways
    Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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