TDGF1 antibody (N-Term)

Catalog No. ABIN1077401

Product Details anti-TDGF1 Antibody

Target: TDGF1 (Teratocarcinoma-Derived Growth Factor 1 (TDGF1))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TDGF1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Purification: Affinity chromatography purified via peptide column

Immunogen: Rabbit polyclonal TDGF1 antibody was raised against a 17 amino acid peptide near the amino terminus of human TDGF1.

Isotype: IgG

Application Details

Application Notes: TDGF1 antibody can be used for detection of TDGF1 by Western blot at 1 - 2 μg/mL. For immunofluorescence start at 20 μg/mL.

Comment:

(NT) Teratocarcinomaderived growth factor 1

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Storage: 4 °C

Storage Comment: TDGF1 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Expiry Date: 12 months

Target Details for TDGF1

Target: TDGF1 (Teratocarcinoma-Derived Growth Factor 1 (TDGF1))

Alternative Name: TDGF1 (TDGF1 Products)

Synonyms: CR antibody, CRGF antibody, CRIPTO antibody, CR1 antibody, cripto antibody, cb85 antibody, tdgf1 antibody, wu:fe01d04 antibody, zgc:109829 antibody, Cripto-1 antibody, cr1 antibody, cr1a antibody, frl-1 antibody, frl1 antibody, xcr1 antibody, TDGF1 antibody, tdgf3 antibody, cripto-3 antibody, teratocarcinoma-derived growth factor 1 antibody, teratocarcinoma-derived growth factor 1, member 3 L homeolog antibody, teratocarcinoma-derived growth factor 1, member 1 antibody, TDGF1 antibody, Tdgf1 antibody, tdgf1 antibody, tdgf1.3.L antibody, tdgf1.1 antibody

Background: Teratocarcinoma-derived growth factor 1 (TDGF1 or Cripto) is a member of the epidermal growth factor-cripto FRL1 cryptic protein family and is involved in the activation of several different signaling pathways during embryonic development and cellular transformation. It is first expressed in the forming mesoderm during gastrulation but later in development the expression is restricted to the truncus arteriosus of the developing heart. This suggests that TDGF1 mediates the progression of epiblastic cells that give rise to the mesoderm. TDGF1 overexpression is characteristic of human gastric and colorectal carcinomas.
Synonyms: Teratocarcinomaderived growth factor 1, Epidermal growth factor-like cripto protein CR1, Cripto-1 growth factor, CRGF, CR, CRGF, CRIPTO, Cripto-1

Molecular Weight: 21 kDa

Gene ID: 6997

NCBI Accession: NP_003203

Pathways: EGFR Signaling Pathway