PUMA antibody
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- Target See all PUMA (BBC3) Antibodies
- PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Monoclonal
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Conjugate
- This PUMA antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Monoclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- A synthesized peptide derived from human PUMA
- Isotype
- IgG
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anti-BCL2 Binding Component 3 (BBC3) (C-Term) antibody
BBC3 Reactivity: Human WB, ICC, IF Host: Rabbit Polyclonal unconjugated
anti-BCL2 Binding Component 3 (BBC3) (AA 131-180) antibodyBBC3 Reactivity: Human, Rat, Pig WB, ELISA, FACS, IP, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-BCL2 Binding Component 3 (BBC3) (AA 119-154) antibodyBBC3 Reactivity: Human WB, FACS, IHC (p), IF Host: Rabbit Polyclonal RB01353 unconjugated
anti-BCL2 Binding Component 3 (BBC3) (AA 119-154) antibodyBBC3 Reactivity: Human WB, ELISA, IHC, FACS, IF Host: Rabbit Polyclonal unconjugated
anti-BCL2 Binding Component 3 (BBC3) (N-Term) antibodyBBC3 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
anti-BCL2 Binding Component 3 (BBC3) (C-Term) antibody (PE)BBC3 Reactivity: Human WB, ICC, IF Host: Rabbit Polyclonal PE
anti-BCL2 Binding Component 3 (BBC3) (C-Term) antibody (PerCP)BBC3 Reactivity: Human WB, ICC, IF Host: Rabbit Polyclonal PerCP
anti-BCL2 Binding Component 3 (BBC3) (N-Term) antibody (Biotin)BBC3 Reactivity: Human WB, IHC Host: Rabbit Polyclonal Biotin
anti-BCL2 Binding Component 3 (BBC3) (BH3 Domain), (C-Term) antibodyBBC3 Reactivity: Human, Mouse WB, FACS, IHC (p), IF, EIA Host: Rabbit Polyclonal unconjugated
anti-BCL2 Binding Component 3 (BBC3) (AA 109-137) antibodyBBC3 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB33714 unconjugated
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- Application Notes
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
- Alternative Name
- BBC3 (BBC3 Products)
- Synonyms
- BBC3 antibody, Puma antibody, JFY-1 antibody, JFY1 antibody, PUMA antibody, PUMA/JFY1 antibody, BCL2 binding component 3 antibody, Bcl-2 binding component 3 antibody, BBC3 antibody, Bbc3 antibody, bbc3 antibody
- Background
- This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011],JFY-1, JFY1, PUMA,Apoptosis,Apoptosis_Mitochondrial Control of Apoptosis,Cell Biology & Developmental Biology,Endocrine & Metabolism,Neurodegenerative Diseases,Neuroscience,BBC3
- Molecular Weight
- 18 kDa
- Gene ID
- 27113
- UniProt
- Q96PG8, Q9BXH1
- Pathways
- p53 Signaling, Positive Regulation of Endopeptidase Activity
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