ZDHHC20 antibody (AA 241-365)

Catalog No. ABIN1714434

Product Details anti-ZDHHC20 Antibody

Target: ZDHHC20 (Zinc Finger, DHHC-Type Containing 20 (ZDHHC20))

Binding Specificity: AA 241-365

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZDHHC20 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DHHC-20

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for ZDHHC20

Target: ZDHHC20 (Zinc Finger, DHHC-Type Containing 20 (ZDHHC20))

Alternative Name: DHHC-20 (ZDHHC20 Products)

Synonyms: 5033406L14Rik antibody, AI448102 antibody, B230110O18Rik antibody, HK11 antibody, RGD1305755 antibody, zinc finger DHHC-type containing 20 antibody, zinc finger, DHHC domain containing 20 antibody, zinc finger, DHHC-type containing 20 antibody, ZDHHC20 antibody, Zdhhc20 antibody

Background:

Synonyms: DHHC-20, Probable palmitoyltransferase ZDHHC20, ZDH20CHUMAN, ZDHHC20, Zinc finger DHHC domain-containing protein 20.

Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZDHHC20 (zinc finger, DHHC-type containing 20) is a 365 amino acid multi-pass membrane protein that contains one DHHC-type zinc finger and is thought to function as a palmitoyltransferase, catalyzing the transformation of palmitoyl-CoA and a cysteine-conjugated protein to an S-palmitoyl protein and free CoA. In response to DNA damage, ZDHHC20, which exists as multiple alternatively spliced isoforms, may be phosphorylated by ATM or ATR. The gene encoding ZDHHC20 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4 % of the human genome.

Gene ID: 253832