ZDHHC20 antibody (Internal Region)

Catalog No. ABIN6258555

Product Details anti-ZDHHC20 Antibody

Target: ZDHHC20 (Zinc Finger, DHHC-Type Containing 20 (ZDHHC20))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZDHHC20 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity: ZDHHC20 Antibody detects endogenous levels of total ZDHHC20.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ZDHHC20, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for ZDHHC20

Target: ZDHHC20 (Zinc Finger, DHHC-Type Containing 20 (ZDHHC20))

Alternative Name: ZDHHC20 (ZDHHC20 Products)

Synonyms: 5033406L14Rik antibody, AI448102 antibody, B230110O18Rik antibody, HK11 antibody, RGD1305755 antibody, zinc finger DHHC-type containing 20 antibody, zinc finger, DHHC domain containing 20 antibody, zinc finger, DHHC-type containing 20 antibody, ZDHHC20 antibody, Zdhhc20 antibody

Background:

Description: Catalyzes palmitoylation of Cys residues on target proteins (PubMed:27153536, PubMed:29326245). Catalyzes palmitoylation of Cys residues in the cytoplasmic C-terminus of EGFR, and modulates the duration of EGFR signaling by modulating palmitoylation-dependent EGFR internalization and degradation (PubMed:27153536). Has a preference for acyl-CoA with C16 fatty acid chains (PubMed:29326245). Can also utilize acyl-CoA with C14 and C18 fatty acid chains (PubMed:29326245).

Gene: ZDHHC20

Molecular Weight: 37 kDa

Gene ID: 253832

UniProt: Q5W0Z9