POLD2 antibody (AA 201-300)

Catalog No. ABIN1714997

Product Details anti-POLD2 Antibody

Target: POLD2 (Polymerase (DNA Directed), delta 2, Accessory Subunit (POLD2))

Binding Specificity: AA 201-300

Reactivity: Macaque

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLD2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Macaque

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DNA polymerase delta p50

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for POLD2

Target: POLD2 (Polymerase (DNA Directed), delta 2, Accessory Subunit (POLD2))

Alternative Name: DNA polymerase delta p50 (POLD2 Products)

Synonyms: 50kDa antibody, p50 antibody, po1D2 antibody, cdc1 antibody, si:dz150f13.3 antibody, zgc:55633 antibody, zgc:77043 antibody, DNA polymerase delta 2, accessory subunit antibody, polymerase (DNA directed), delta 2, regulatory subunit antibody, polymerase (DNA directed), delta 2, accessory subunit L homeolog antibody, POLD2 antibody, Pold2 antibody, pold2.L antibody, pold2 antibody

Background:

Synonyms: DNA polymerase delta subunit 2, DNA polymerase delta subunit p50, DNA polymerase subunit delta 2, DNA polymerase subunit delta p50, DPOD2_HUMAN, POLD 2, POLD2.

Background: This gene encodes the 50- kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein is required for the stimulation of DNA polymerase delta activity by the processivity cofactor proliferating cell nuclear antigen (PCNA). Expression of this gene may be a marker for ovarian carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Mar 2012].

Gene ID: 5425

Pathways: Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA