MLXIPL antibody (AA 18-143)
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- Target See all MLXIPL Antibodies
- MLXIPL (MLX Interacting Protein-Like (MLXIPL))
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Binding Specificity
- AA 18-143
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This MLXIPL antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
- Purification
- purified
- Immunogen
- Purified recombinant fragment of human MLXIPL (AA: 18-143) expressed in E. coli.
- Clone
- 5D12D1
- Isotype
- IgG1
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- Application Notes
- ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
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Glucose-induced nuclear shuttling of ChREBP is mediated by sorcin and Ca(2+) ions in pancreatic β-cells." in: Diabetes, Vol. 61, Issue 3, pp. 574-85, (2012) (PubMed).
: "ChREBP expression in the liver, adipose tissue and differentiated preadipocytes in human obesity." in: Biochimica et biophysica acta, Vol. 1811, Issue 12, pp. 1194-200, (2011) (PubMed).
: "
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Glucose-induced nuclear shuttling of ChREBP is mediated by sorcin and Ca(2+) ions in pancreatic β-cells." in: Diabetes, Vol. 61, Issue 3, pp. 574-85, (2012) (PubMed).
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- Target
- MLXIPL (MLX Interacting Protein-Like (MLXIPL))
- Alternative Name
- MLXIPL (MLXIPL Products)
- Synonyms
- ChREBP antibody, MLXIPL antibody, CHREBP antibody, MIO antibody, MONDOB antibody, WBSCR14 antibody, WS-bHLH antibody, bHLHd14 antibody, Wbscr14 antibody, MLX interacting protein-like antibody, MLX interacting protein like antibody, MLXIPL antibody, Mlxipl antibody
- Background
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Description: This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. , , , ,
Aliases: MIO, CHREBP, MONDOB, WBSCR14, WS-bHLH, bHLHd14
- Molecular Weight
- 93.1 kDa
- Gene ID
- 51085
- HGNC
- 51085
- Pathways
- Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
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