HMGB1 antibody (meLys42, N-Term)
-
- Target See all HMGB1 Antibodies
- HMGB1 (High Mobility Group Box 1 (HMGB1))
-
Binding Specificity
- meLys42, N-Term
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This HMGB1 antibody is un-conjugated
-
Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Specificity
- Reacts with HMGB1 methylated on Lysine 42 from human neutrophils
- Cross-Reactivity (Details)
- Not tested in other species. May cross react with a wide range of species due to sequence homology.
- Purification
- Antiserum
- Immunogen
- Synthetic peptide derived from N terminal region of HMGB1, containing mono-methyl at K42
- Isotype
- IgG
- Top Product
- Discover our top product HMGB1 Primary Antibody
-
-
- Application Notes
-
Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
IHC1:100 - 1:1000 WB1:200 - Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Must be reconstituted in distilled water.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
- Expiry Date
- 24 months
-
- Target
- HMGB1 (High Mobility Group Box 1 (HMGB1))
- Alternative Name
- HMGB1 (HMGB1 Products)
- Synonyms
- HMG1 antibody, HMG3 antibody, SBP-1 antibody, DEF antibody, HMG-1 antibody, Hmg1 antibody, amphoterin antibody, p30 antibody, hmgb1 antibody, ik:tdsubc_1a5 antibody, wu:fb23c02 antibody, xx:tdsubc_1a5 antibody, zgc:56110 antibody, zgc:77104 antibody, hmg-1 antibody, hmg3 antibody, sbp-1 antibody, hmg1 antibody, HMGB1 antibody, Ac2-008 antibody, high mobility group box 1 antibody, high-mobility group box 1 antibody, high mobility group box 1a antibody, high mobility group box 1 L homeolog antibody, high mobility group protein B1 antibody, HMGB1 antibody, Hmgb1 antibody, hmgb1 antibody, hmgb1a antibody, hmgb1.L antibody, LOC100359149 antibody
- Background
- HMGB1 is a DAMP involved in innate immune response. It is secreted by activated dendritic cells, macrophages and necrotic cells.
- Gene ID
- 3146
- UniProt
- P09429
- Pathways
- p53 Signaling, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, Inflammasome
-