PTPN11 antibody (AA 520-547)

Catalog No. ABIN1810107

The Rabbit Polyclonal anti-PTPN11 antibody (ABIN1810107) specifically detects PTPN11 in WB, IHC, IHC (p) and FACS. The antibody is reactive with Human and Mouse samples.

Quick Overview for PTPN11 antibody (AA 520-547) (ABIN1810107)

Target: PTPN11 (Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPN11 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-PTPN11 Antibody

Binding Specificity: AA 520-547

Specificity: This PTPN11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 520-547 amino acids from the C-terminal region of human PTPN11.

Purification: Ammonium sulfate precipitation

Application Details

Application Notes: Approved: Flo (1:10 - 1:50), IHC, IHC-P (1:50 - 1:100), WB (1:1000)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.

Expiry Date: 6 months

Target Details for PTPN11

Target: PTPN11 (Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11))

Alternative Name: PTPN11 / SHP-2 / NS1

Background: Name/Gene ID: PTPN11
Subfamily: NT2
Family: Protein Phosphatase

Synonyms: PTPN11, Bptp-3, BPTP3, CFC, Csw, Corkscrew csw, Gene corkscrew, Phosphatase corkscrew, PTP-2C, SHP2, PTP-1D, PTP2C, SHP-2, SHPTP2, Noonan syndrome 1, SH-PTP2, SH-PTP3

Gene ID: 5781

UniProt: Q06124

Pathways: JAK-STAT Signaling, RTK Signaling, TCR Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, BCR Signaling, Warburg Effect