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TRAIL antibody (AA 95-281)

TNFSF10 Reactivity: Human WB, FACS, Func Host: Mouse Monoclonal 2E5 unconjugated
Catalog No. ABIN6796422
  • Target See all TRAIL (TNFSF10) Antibodies
    TRAIL (TNFSF10) (Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10))
    Binding Specificity
    • 15
    • 9
    • 7
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 95-281
    Reactivity
    • 102
    • 32
    • 30
    • 4
    • 2
    Human
    Host
    • 79
    • 41
    • 1
    Mouse
    Clonality
    • 82
    • 39
    Monoclonal
    Conjugate
    • 65
    • 15
    • 10
    • 6
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TRAIL antibody is un-conjugated
    Application
    • 91
    • 36
    • 23
    • 22
    • 13
    • 13
    • 9
    • 9
    • 9
    • 8
    • 7
    • 6
    • 6
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Functional Studies (Func)
    Specificity
    TRAIL is a cytotoxic protein closely related to Fas (CD95), which induces extensive apoptosis in a range of cell types. TRAIL induces apoptosis via the receptors DR4 and DR5. Most normal tissues are resistant to TRAIL induced apoptosis due to their expression of decoy receptors, DcR1 and DcR2, which antagonize TRAIL activity. TRAIL is expressed by cell lines, activated lymphocytes and on syncytiotrophoblast cells in first trimester pregnancy. This antibody neutralizes TRAIL activity.
    Purification
    Protein A purified
    Immunogen
    Recombinant human CD253 (TRAIL) aa 95-281.
    ImmunogenType: Recombinant protein
    Clone
    2E5
    Isotype
    IgG1
    Top Product
    Discover our top product TNFSF10 Primary Antibody
  • Restrictions
    For Research Use only
  • Concentration
    Lot specific
    Buffer
    PBS
    Storage
    -20 °C
    Storage Comment
    Store at -20°C.
  • Target
    TRAIL (TNFSF10) (Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10))
    Alternative Name
    TNFSF10 / TRAIL (TNFSF10 Products)
    Synonyms
    APO2L antibody, Apo-2L antibody, CD253 antibody, TL2 antibody, TRAIL antibody, A330042I21Rik antibody, AI448571 antibody, APO-2L antibody, Ly81 antibody, Trail antibody, tl2 antibody, apo2l antibody, cd253 antibody, trail antibody, apo-2l antibody, trail1 antibody, xtrail1 antibody, tnfsf10l2 antibody, zgc:92320 antibody, TNLG6A antibody, TNF superfamily member 10 antibody, tumor necrosis factor (ligand) superfamily, member 10 antibody, tumor necrosis factor superfamily member 10 antibody, TNF superfamily member 10 S homeolog antibody, TNFSF10 antibody, Tnfsf10 antibody, tnfsf10.S antibody, tnfsf10 antibody
    Background
    Synonyms :
    TNFSF10, Apo-2L, APO2L, Apo-2 ligand, CD253, CD253 antigen, TRAIL, Protein TRAIL, TL2
    Gene ID
    8743
    Pathways
    Apoptosis, Positive Regulation of Endopeptidase Activity
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