Factor VII antibody

Catalog No. ABIN1820039

Product Details anti-Factor VII Antibody

Target: Factor VII (F7) (Coagulation Factor VII (F7))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Factor VII antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Radioimmunoassay (RIA)

Specificity: Recognizes Factor VII, a serine protease found circulating in the blood. It initiates the extrinsic pathway of blood coagulation in conjunction with tissue factor. Tissue factor is found on the outside of blood vessels. When the vessels is damaged, tissue factor is exposed to the blood and circulating Factor VII. Once bound to tissue factor, Factor VII is activated by different proteases and converts Factor IX to IXa. Factor VII deficiency is a rare hereditary hemorrhagic disease. Symptoms range from mild to severe. Clone RFF-VII/1 is a strong inhibitor of Factor VII activity. It may be used to detect Factor VII in immunoassays in combination with clone RFF-VII/2 as a capture reagent.

Purification: Protein G purified

Immunogen: Purified Factor VII.

Type of Immunogen: Purified protein

Clone: RFF-VII-1

Isotype: IgG1

Application Details

Application Notes: Approved: ELISA (1:20 - 1:200), RIA, WB

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: 4°C or -20°C, Avoid freeze-thaw cycles.

Target Details for Factor VII

Target: Factor VII (F7) (Coagulation Factor VII (F7))

Alternative Name: F7 / Factor VII (F7 Products)

Synonyms: F7 antibody, wu:fb59f04 antibody, zgc:109870 antibody, SPCA antibody, AI114908 antibody, ATIII antibody, At-3 antibody, At3 antibody, LOC100223776 antibody, AI132620 antibody, Cf7 antibody, FVII antibody, mfVII antibody, f7 antibody, coagulation factor VII antibody, serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 antibody, coagulation factor 7 (serum prothrombin conversion accelerator) S homeolog antibody, F7 antibody, f7 antibody, Serpinc1 antibody, CpipJ_CPIJ009142 antibody, CpipJ_CPIJ010295 antibody, CpipJ_CPIJ020127 antibody, fa7 antibody, f7.S antibody

Background: Name/Gene ID: F7
Subfamily: Serine S1
Family: Protease

Synonyms: F7, Coagulation factor VII, Eptacog alfa, F7 Deficiency, Factor 7, Factor VIIa, FVII coagulation protein, Factor VII, FVII, SPCA, Factor VII Deficiency, Proconvertin

Gene ID: 2155

Pathways: Response to Growth Hormone Stimulus, Platelet-derived growth Factor Receptor Signaling