PML antibody

Catalog No. ABIN1821373

Product Details anti-PML Antibody

Target: PML (Promyelocytic Leukemia (PML))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PML antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: Normal PML proteins of lower molecular weight, and also recognizes the high molecular weight PML/RAR alpha chimeric protein in promyelocytic leukemia patients.

Purification: Affinity purified

Immunogen: Recombinant corresponding to partial human PML.

Type of Immunogen: Recombinant protein

Clone: GF1

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: distilled water to 1 mg/mL.

Concentration: Lot specific

Buffer: Lyophilized from 0.01 M PBS,  pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Lyophilized powder may be stored at -20°C. Stable for 1 year at -20°C. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Reconstituted product is stable for 1 year at -20°C.

Target Details for PML

Target: PML (Promyelocytic Leukemia (PML))

Alternative Name: PML (PML Products)

Synonyms: MYL antibody, PP8675 antibody, RNF71 antibody, TRIM19 antibody, 1200009E24Rik antibody, AI661194 antibody, Trim19 antibody, RGD1562602 antibody, PML antibody, promyelocytic leukemia antibody, PML antibody, Pml antibody

Background: Name/Gene ID: PML
Family: Transcription factor

Synonyms: PML, PP8675, Promyelocytic leukemia, Protein PML, TRIM19, Promyelocytic leukemia protein, RING finger protein 71, MYL, RNF71

Gene ID: 5371

UniProt: P29590

Pathways: p53 Signaling, Retinoic Acid Receptor Signaling Pathway, Maintenance of Protein Location, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus