IFIH1 antibody (Arg470)

Catalog No. ABIN1822663

Product Details anti-IFIH1 Antibody

Target: IFIH1 (Interferon Induced with Helicase C Domain 1 (IFIH1))

Binding Specificity: Arg470

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This IFIH1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Specificity: Endogenous levels of total MDA-5. Species Crossreactivity: mouse.

Purification: Purified

Immunogen: Synthetic peptide corresponding to residues surrounding Arg470 of human MDA-5.

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: IP (1:100), WB

Usage: Western Blot: 1:1000 Incubate membrane with diluted antibody in 5 % BSA, 1X TBS, 0.1 % Tween-20 at 4 °C with gentle shaking, overnight.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 10 mM sodium HEPES,  pH 7.5, 150 mM sodium chloride, 100 μg/mL BSA, less than 0.02 % sodium azide, 50 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: May be stored at 4°C for short-term only. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Aliquots are stable for at least 1 year.

Target Details for IFIH1

Target: IFIH1 (Interferon Induced with Helicase C Domain 1 (IFIH1))

Alternative Name: IFIH1 / MDA5 (IFIH1 Products)

Synonyms: MDA5 antibody, Hlcd antibody, IDDM19 antibody, MDA-5 antibody, RLR-2 antibody, 9130009C22Rik antibody, Helicard antibody, RGD1560496 antibody, interferon induced with helicase C domain 1 antibody, IFIH1 antibody, Ifih1 antibody

Background: Name/Gene ID: IFIH1
Family: DEAD box protein

Synonyms: IFIH1, Helicase with 2 CARD domains, MDA-5, MDA5, Helicard, IDDM19, RLR-2, RH116, CADM-140 autoantigen, Hlcd, RIG-I-like receptor 2

Gene ID: 64135

UniProt: Q9BYX4

Pathways: Activation of Innate immune Response