CDKN2B antibody (AA 61-71)

Catalog No. ABIN1834022

Product Details anti-CDKN2B Antibody

Target: CDKN2B (Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B))

Binding Specificity: AA 61-71

Reactivity: Human, Monkey

Host: Goat

Clonality: Polyclonal

Conjugate: This CDKN2B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: Human CDKN2B / p15 INK4b. This antibody is expected to recognize isoform 2 (NP_511042.1) only.

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-RQGARERGARP from the C-terminus of human CDKN2B / p15 INK4b (NP_004927.2, NP_511042.1). Percent identity by BLAST analysis: Human, Marmoset (100%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: Peptide-ELISA (1:128000), WB (1 - 3 μg/mL)

Usage: Peptide ELISA: antibody detection limit dilution 1:128000. Western blot: Approx 12+14kD bands observed in Human Gastrointestinal cancer lysates (calculated MW of 8.1kD according to NP_511042.1). The observed 14kD cannot represent isoform 1 and therefore it most likely represents another post translational modification of isoform 2. Recommended concentration: 1-3 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for CDKN2B

Target: CDKN2B (Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B))

Alternative Name: CDKN2B / p15 INK4b (CDKN2B Products)

Synonyms: p14-INK4b antibody, cdk4l antibody, ink4b antibody, mts2 antibody, p15 antibody, p15ink4b antibody, tp15 antibody, CDK4I antibody, INK4B antibody, MTS2 antibody, P15 antibody, TP15 antibody, p15INK4b antibody, AV083695 antibody, INK4b antibody, p15(INK4b) antibody, CDKN2A antibody, cyclin dependent kinase inhibitor 2B antibody, Cyclin-dependent kinase 4 inhibitor B antibody, cyclin-dependent kinase inhibitor 2B antibody, cyclin-dependent kinase inhibitor 2B L homeolog antibody, cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) antibody, CDKN2B antibody, cdn2b antibody, cdkn2b antibody, cdkn2b.L antibody, Cdkn2b antibody

Background: Name/Gene ID: CDKN2B

Synonyms: CDKN2B, CDK inhibitory protein, CDK4B inhibitor, INK4B, MTS2, Multiple tumor suppressor 2, p14_INK4B, p15, p14_CDK inhibitor, p15 CDK inhibitor, p15 INK4b, p15-INK4b, p15_INK4B, p14-INK4b, p15INK4b, CDK4I, MTS-2, TP15

Gene ID: 1030

NCBI Accession: NP_004927, NP_511042

UniProt: P42772

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases