MAPKAPK5 antibody, MK5 antibody, PRAK antibody, MAPKAP-K5 antibody, MK-5 antibody, mitogen-activated protein kinase-activated protein kinase 5 antibody, MAP kinase-activated protein kinase 5 antibody, MAPKAPK5 antibody, mapkapk5 antibody, Mapkapk5 antibody
Background
The protein encoded by this gene is a member of the serine/threonine kinase family.In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta.In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites.Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported.[provided by RefSeq]