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IL12RB2 antibody (AA 323-665)
IL12RB2
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-IL12RB2 Antibody
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Target
See all IL12RB2 Antibodies
IL12RB2
(Interleukin 12 Receptor, beta 2 (IL12RB2))
Binding Specificity
All epitopes for IL12RB2 antibodies
AA 323-665
Reactivity
All reactivities for IL12RB2 antibodies
Human
Host
All hosts for IL12RB2 antibodies
Rabbit
Clonality
All clonalities for IL12RB2 antibodies
Polyclonal
Conjugate
All conjugates for IL12RB2 antibodies
This IL12RB2 antibody is un-conjugated
Application
All applications for IL12RB2 antibodies
Western Blotting (WB)
Purification
Purified by antigen-affinity chromatography.
Immunogen
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 323 and 665 of Human IL12RB2
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Discover our top product IL12RB2 Primary Antibody
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Application Details
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Application Notes
Suggested dilutions: Western blotting: 1.500-1.3000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
Preservative
Thimerosal (Merthiolate)
Precaution of Use
Biohazard Informations: This product contains thimerosal which is hazardous.
Storage
4 °C/-20 °C
Storage Comment
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target Details for IL12RB2
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Target
IL12RB2
(Interleukin 12 Receptor, beta 2 (IL12RB2))
Abstract
IL12RB2 Products
Synonyms
IL12RB2 antibody, A930027I18Rik antibody, IL-12RB2 antibody, Ifnm antibody, interleukin 12 receptor subunit beta 2 antibody, interleukin 12 receptor, beta 2 antibody, IL12RB2 antibody, Il12rb2 antibody
Background
The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex.The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling.The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation.The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense.[provided by RefSeq]
Molecular Weight
97 kDa
Gene ID
3595
NCBI Accession
NM_001559 , NP_001550
Pathways
JAK-STAT Signaling
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