FKBP15 antibody (N-Term)

Catalog No. ABIN1887901

Product Details anti-FKBP15 Antibody

Target: FKBP15 (FK506 Binding Protein 15, 133kDa (FKBP15))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FKBP15 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide from near the amino terminus of human FKBP15.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for FKBP15

Target: FKBP15 (FK506 Binding Protein 15, 133kDa (FKBP15))

Alternative Name: FKBP15 (FKBP15 Products)

Synonyms: KIAA0674 antibody, DKFZp469F024 antibody, BB131447 antibody, C430014M02Rik antibody, FKBO133 antibody, FKBP-133 antibody, FKBP-15 antibody, FKBP133 antibody, mKIAA0674 antibody, RGD1304816 antibody, PPP1R76 antibody, FK506 binding protein 15 antibody, si:ch211-208h16.4 antibody, FKBP15 antibody, si:ch211-208h16.4 antibody, Fkbp15 antibody

Background: FKBP15, also known as FKBP133, is a member of the FK506-binding protein family, a group of proteins initially identified as immunophilins, targets for the immunosupressant drugs FK506 and Rapamycin.FKBP15 is expressed in the developing nervous system and contains a domain similar to Wiskott-Aldrich syndrome protein homology region 1 (WH1) in addition to the FK506-binding protein motif.FKBP15 is distributed along the axonal shafts and partially co-localizes with F-actin in the growth cones of dorsal root ganglion neurons, overexpression of FKBP15 resulted in the number of filopodia in transfected neurons, suggesting that FKBP15 modulates growth cone behavior.FKBP15 has also been shown to associate with both microtubules and the actin filament systems and disruption of its expression by RNAi resulted in delayed transport of early endosomes in HeLa cells indicating that FKBP15 is also involved in the transport of early endosomes.At least three isoforms of FKBP15 are known to exist.
Synonyms: FKBP15, FK506-binding protein homolog, FKBP133, WASP and FKBP-like, WAFL

NCBI Accession: NP_056073

Pathways: SARS-CoV-2 Protein Interactome