PTPN11 antibody (AA 543-593)

Catalog No. ABIN1927986

The Rabbit Polyclonal anti-PTPN11 antibody (ABIN1927986) specifically detects PTPN11 in WB and IP. The antibody is reactive with Human, Mouse, Cow, Rabbit, Chicken, Horse and Xenopus laevis samples.

Quick Overview for PTPN11 antibody (AA 543-593) (ABIN1927986)

Target: PTPN11 (Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11))

Reactivity: Human, Mouse, Cow, Rabbit, Chicken, Horse, Xenopus laevis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPN11 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-PTPN11 Antibody

Binding Specificity: AA 543-593

Specificity: Region between residue 543 and 593 of human tyrosine-protein phosphatase non-receptor type 11 using the numbering given in entry NP_002825.3 (GeneID 5781).

Purification: Immunoaffinity purified

Isotype: IgG

Application Details

Application Notes: Approved: IP (2 - 5 μg/mg lysate), WB (1:2000 - 1:10000)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-citrate/phosphate buffer,  pH 7-8, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C for up to 1 year.

Expiry Date: 12 months

Target Details for PTPN11

Target: PTPN11 (Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11))

Alternative Name: PTPN11 / SHP-2 / NS1

Background: Name/Gene ID: PTPN11
Subfamily: NT2
Family: Protein Phosphatase

Synonyms: PTPN11, Bptp-3, BPTP3, CFC, Csw, Corkscrew csw, Gene corkscrew, Phosphatase corkscrew, PTP-2C, SHP2, PTP-1D, PTP2C, SHP-2, SHPTP2, Noonan syndrome 1, SH-PTP2, SH-PTP3

Gene ID: 5781

Pathways: JAK-STAT Signaling, RTK Signaling, TCR Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, BCR Signaling, Warburg Effect