TLR4 antibody (C-Term)

Catalog No. ABIN198154

Product Details anti-TLR4 Antibody

Target: TLR4 (Toll-Like Receptor 4 (TLR4))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLR4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: This antibody, specific for human TLR4, shows a positive result for ELISA and detects 2-3 protein species of ~70 to ~100kD on Western blot analysis using human placenta tissue homogenate, JEG-3 placenta choriocarcinoma, U-937 histocytic lymphoma, BC-1 human B-lymphocyte lymphoma, Nalm-6-pre-B lymphocyte and REH pre-B lymphocyte cell lysates. Reactivity has been confirmed with human placenta tissue homogenate, JEG-3 placenta choriocarcinoma, U-937 histocytic lymphoma, BC-1 human B-lymphocyte lymphoma, Nalm-6-pre-B lymphocyte and REH pre-B lymphocyte cell lysates. This antibody should be theoretically reactive to gorilla, orangutan and chimpanzee TRL4 due to amino acid homology.

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide derived from the carboxyl termini of various human TLR4 (Toll-like receptor 4) isoforms A-D.

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: ELISA (0.1 - 1 μg/mL), WB (1 - 3 μg/mL)

Usage: Suitable for use in ELISA and Western Blot. ELISA: 0.1-1 μg/mL. Western Blot: 1-3 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.

Target Details for TLR4

Target: TLR4 (Toll-Like Receptor 4 (TLR4))

Alternative Name: TLR4 (TLR4 Products)

Synonyms: ARMD10 antibody, CD284 antibody, TLR-4 antibody, TOLL antibody, Lps antibody, Ly87 antibody, Ran/M1 antibody, Rasl2-8 antibody, toll like receptor 4 antibody, toll-like receptor 4 antibody, TLR4 antibody, Tlr4 antibody

Background: Name/Gene ID: TLR4
Family: Toll-like Receptor

Synonyms: TLR4, CD284, CD284 antigen, Homolog of Drosophila toll, TLR-4, TOLL, ARMD10, Toll-like receptor 4, HToll

Gene ID: 7099

UniProt: O00206

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins