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Integrin Alpha2b antibody

CD41 Reactivity: Human, Primate FACS, IHC, IHC (fro) Host: Mouse Monoclonal HIP8 unconjugated
Catalog No. ABIN207081
  • Target See all Integrin Alpha2b (CD41) Antibodies
    Integrin Alpha2b (CD41)
    Reactivity
    • 107
    • 29
    • 21
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
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    Human, Primate
    Host
    • 66
    • 43
    • 20
    Mouse
    Clonality
    • 83
    • 40
    • 1
    Monoclonal
    Conjugate
    • 54
    • 14
    • 12
    • 11
    • 4
    • 4
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    • 2
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    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Integrin Alpha2b antibody is un-conjugated
    Application
    • 93
    • 42
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    • 18
    • 18
    • 13
    • 13
    • 10
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    • 8
    • 5
    • 3
    • 1
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    • 1
    Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificity
    Reacts with alpha (a) subunit of CD41 (heavy chain, 120 kD). CD41 is mainly expressed on platelets and megakaryocytes. The antibody HIP8 blocks platelet aggregation and completely inhibits ADP-, epinephrine-, and collagen-induced platelet activation, and partially inhibits ristocetin- and thrombin-induced platelet activation. HIP8 is useful in the morphological and physiological studies of platelets and megakaryocytes.
    Purification
    Protein G purified
    Immunogen


    Type of Immunogen: Native protein
    Clone
    HIP8
    Isotype
    IgG1
    Top Product
    Discover our top product CD41 Primary Antibody
  • Application Notes
    Approved: Flo, IHC, IHC-Fr

    Usage: Flow Cytometry: This HIP8 antibody has been tested by flow cytometric analysis of human platelets. This can be used at less than or equal to 0.5 μg per 100 μL blood (per 106cells).

    Not recommended for: IHC-P
    Comment

    Target Species of Antibody: Human

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    PBS, 15 mM sodium azide, approx,  pH 7.4.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C,-20 °C
    Storage Comment
    4°C or -20°C, Avoid freeze-thaw cycles.
  • Target
    Integrin Alpha2b (CD41)
    Alternative Name
    ITGA2B / CD41 (CD41 Products)
    Synonyms
    AI172977 antibody, CD41 antibody, CD41B antibody, GpIIb antibody, alphaIIb antibody, BDPLT16 antibody, BDPLT2 antibody, GP2B antibody, GPIIb antibody, GT antibody, GTA antibody, HPA3 antibody, integrin alpha 2b antibody, integrin subunit alpha 2b antibody, Itga2b antibody, ITGA2B antibody
    Background
    Name/Gene ID: ITGA2B
    Family: Integrin

    Synonyms: ITGA2B, BDPLT2, CD41B, GT, gp2B, Integrin alpha-IIb, ITGAB, GPIIb, HPA3, Platelet-specific antigen BAK, CD41, CD41 antigen, GPalpha IIb, GTA
    Gene ID
    3674
    UniProt
    P08514
    Pathways
    Integrin Complex
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