HLAG antibody (Biotin)

Catalog No. ABIN207212

The Mouse Monoclonal anti-HLAG antibody is suitable to detect HLAG in samples from Human. It has been validated for ELISA and FACS.

Quick Overview for HLAG antibody (Biotin) (ABIN207212)

Target: HLAG (HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HLAG antibody is conjugated to Biotin

Application: ELISA, Flow Cytometry (FACS)

Clone: 87G

Product Details anti-HLAG Antibody (Biotin)

Specificity: Recognizes both membrane-bound and soluble forms of HLA-G (HLA-G1 and HLA-G5). HLA-G belongs to the MHC Class I molecules (MHC Class Ib, nonclassical) and it is expressed on the surface of trophoblast cells. The antibody 87G blocks interaction of HLA-G with inhibitory receptors

Purification: Purified

Immunogen: H-2 identical murine cells transfected with and expressing genes encoding HLA-G and human beta2-microglobulin.

Isotype: IgG2a

Application Details

Application Notes: Approved: ELISA, Flo

Usage: The reagent is designed for Flow Cytometry analysis of cells expressing HLA-G molecule on the cell surface, and for ELISA. Suggested working dilution for Flow Cytometry is 1:500. Indicated dilution is recommended starting point for use of this product. Wo The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 15 mM sodium azide, approx,  pH 7.4.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.

Target Details for HLAG

Target: HLAG (HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG))

Alternative Name: HLA-G

Background: Name/Gene ID: HLA-G

Synonyms: HLA-G, HLAG, HLA-6.0, MHC class I antigen G, HLA G antigen

Gene ID: 3135

UniProt: P17693

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints, Human Leukocyte Antigen (HLA) in Adaptive Immune Response