MLH1 antibody (AA 387-403)

Catalog No. ABIN208109

Product Details anti-MLH1 Antibody

Target: MLH1 (MutL Homolog 1 (MLH1))

Binding Specificity: AA 387-403

Reactivity: Human, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This MLH1 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: In Molt-4, a 83 kD band is observed.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla, Monkey, Marmoset (100%) Gibbon (94%) Elephant, Panda, Bat, Dog, Rabbit (88%) Mouse, Hamster, Bovine, Horse, Pig, Opossum, Turkey, Chicken, Lizard, Xenopus (82%).

Purification: Protein G purified

Immunogen: This antibody was generated by immunizing mice with a synthetic peptide corresponding to amino acids 387-403 DSREQKLDAFLQPLSKP of human MLH1, GenBank no. NP_000240.1. This peptide sequence is 93% homologous to mouse and dog MLH1. Percent identity by BLAST analysis: Human, Gorilla, Monkey, Marmoset (100%), Gibbon (94%), Elephant, Panda, Bat, Dog, Rabbit (88%), Mouse, Hamster, Bovine, Horse, Pig, Opossum, Turkey, Chicken, Lizard, Xenopus (82%).

Type of Immunogen: Synthetic peptide

Clone: 164C819

Isotype: IgG

Application Details

Application Notes: Approved: WB (2 - 3 μg/mL)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.2 % gelatin, 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for MLH1

Target: MLH1 (MutL Homolog 1 (MLH1))

Alternative Name: MLH1 (MLH1 Products)

Synonyms: CG11482 antibody, Dmel\\CG11482 antibody, dmlh-1 antibody, dmlh1 antibody, zgc:66301 antibody, MLH1 antibody, LOC100232198 antibody, 1110035C23Rik antibody, AI317206 antibody, AI325952 antibody, AI561766 antibody, COCA2 antibody, FCC2 antibody, HNPCC antibody, HNPCC2 antibody, hMLH1 antibody, mutL homolog 1 antibody, CG11482 gene product from transcript CG11482-RB antibody, mutL homolog 1 S homeolog antibody, mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) antibody, DNA mismatch repair protein Mlh1 antibody, MLH1 antibody, Mlh1 antibody, mlh1.S antibody, mlh1 antibody, LOC588545 antibody

Background: Name/Gene ID: MLH1

Synonyms: MLH1, COCA2, FCC2, HMLH1, HNPCC, HNPCC2, MutL protein homolog 1

Gene ID: 4292

NCBI Accession: NP_000240

UniProt: P40692

Pathways: DNA Damage Repair, Production of Molecular Mediator of Immune Response