PCSK6 antibody (Internal Region)

Catalog No. ABIN213558

Product Details anti-PCSK6 Antibody

Target: PCSK6 (Proprotein Convertase Subtilisin/kexin Type 6 (PCSK6))

Binding Specificity: Internal Region

Reactivity: Human, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCSK6 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Human PACE4. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Predicted Reactivity: Percent identity with other species by BLAST analysis: Human, Gorilla, Rabbit (100%) Gibbon, Monkey (94%) Marmoset, Mouse, Rat, Bovine, Dog, Elephant, Panda, Horse, Pig, Opossum (88%).

Purification: Immunoaffinity purified

Immunogen: Synthetic 17 amino acid peptide from internal region of human PACE4. Percent identity with other species by BLAST analysis: Human, Gorilla, Rabbit (100%), Gibbon, Monkey (94%), Marmoset, Mouse, Rat, Bovine, Dog, Elephant, Panda, Horse, Pig, Opossum (88%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: ELISA, IHC, IHC-P (20 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 20 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, less than 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PCSK6

Target: PCSK6 (Proprotein Convertase Subtilisin/kexin Type 6 (PCSK6))

Alternative Name: PACE4 / PCSK6 (PCSK6 Products)

Synonyms: PACE4 antibody, PCSK6 antibody, SPC4 antibody, C86343 antibody, Pace4 antibody, Spc4 antibody, PACE4AIIa antibody, Xpace4 antibody, spc4 antibody, proprotein convertase subtilisin/kexin type 6 antibody, peptidase S8 antibody, proprotein convertase subtilisin/kexin type 6 L homeolog antibody, PCSK6 antibody, EAMY_RS27925 antibody, pcsk6 antibody, Pcsk6 antibody, pcsk6.L antibody

Background: Name/Gene ID: PCSK6
Subfamily: Serine S8
Family: Protease

Synonyms: PCSK6, PACE4, SPC4

Gene ID: 5046

Pathways: Neurotrophin Signaling Pathway, SARS-CoV-2 Protein Interactome