IGF1R antibody (Exon 4)
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- Target See all IGF1R Antibodies
- IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
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Binding Specificity
- AA 4-6, AA 283-440, Exon 4
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Reactivity
- Human, Rabbit
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This IGF1R antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunoprecipitation (IP)
- Specificity
- Recognizes human Insulin-Like Growth Factor I Receptor, alpha (IGF1Ra) at 125kD. Species cross-reactivity: Weakly reacts with rabbit. Does not react with rat.
- Purification
- Protein G purified
- Immunogen
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IGF-1R/3T3 mouse fibroblasts transfected with human type I IGF-receptor cDNA. Epitope: aa283-440 (exon 4-6). Cellular Localization: Cell membrane.
Type of Immunogen: Cells - Isotype
- IgG1
- Top Product
- Discover our top product IGF1R Primary Antibody
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- Application Notes
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Approved: ELISA, IP, WB
Usage: Suitable for use in ELISA, Immunoprecipitation and as a weak IGF-like agonist in bioassays (Thymidine incorporation into DNA). Does not significantly Inhibit IGF-1 Binding. Not suitable for use in Western Blot. Immunoprecipitation: 2 μg/mg protein lysate using Protein G. ELISA: Capture Antibody. Positive control: Placenta or breast carcinoma. - Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.4, 0.2 % BSA, 0.1 % sodium azide, 40 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- Target
- IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
- Alternative Name
- IGF1R / IGF1 Receptor (IGF1R Products)
- Synonyms
- CMT2N antibody, CD221 antibody, IGFIR antibody, IGFR antibody, JTK13 antibody, IGFIRC antibody, IGFR1 antibody, IGF-1R antibody, IGF1R antibody, DKFZp469I0618 antibody, igf-1r antibody, xIGF-1R antibody, xIGFR antibody, xigf1r antibody, A330103N21Rik antibody, D930020L01 antibody, hyft antibody, igf-ir antibody, IGF-IR antibody, IGF-IRb antibody, wu:fb03h06 antibody, IGF-IRa antibody, sb:eu1090 antibody, wu:fi20b10 antibody, alanyl-tRNA synthetase antibody, insulin like growth factor 1 receptor antibody, insulin-like growth factor 1 receptor antibody, insulin-like growth factor 1 antibody, insulin-like growth factor I receptor antibody, insulin like growth factor 1 receptor S homeolog antibody, insulin-like growth factor 1b receptor antibody, insulin-like growth factor 1a receptor antibody, AARS antibody, IGF1R antibody, Igf1r antibody, igf1r antibody, Igf1 antibody, LOC780503 antibody, LOC100136427 antibody, igf1r.S antibody, igf1rb antibody, igf1ra antibody
- Background
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Name/Gene ID: IGF1R
Subfamily: Insulin receptor
Family: Protein Kinase
Synonyms: IGF1R, CD221 antigen, CD221, IGF1 Receptor, IGFR, IGF-I receptor, Soluble IGF1R variant 1, Soluble IGF1R variant 2, Type 1 IGF receptor, IGFIR, JTK13 - Gene ID
- 3480
- UniProt
- P08069
- Pathways
- RTK Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy
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