ERBB3 antibody
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- Target See all ERBB3 Antibodies
- ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This ERBB3 antibody is un-conjugated
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Application
- Immunofluorescence (IF), Flow Cytometry (FACS), Immunoprecipitation (IP)
- Specificity
- Does not block the binding of heregulin to c-erbB-31, has no effect on tyrosine kinase activity1, receptor internalization1, or tumorigenic growth of cells overexpressing the cerbB- 32. It is particularly well suited for immunoprecipitation of unoccupied as well as the occupied receptor1. Species cross-reactivity: human.
- Purification
- Protein A purified
- Immunogen
- Extracellular fragment of recombinant human c-erbB-3/HER-3 oncoprotein.
- Clone
- H3-90-6
- Isotype
- IgG2a
- Top Product
- Discover our top product ERBB3 Primary Antibody
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- Application Notes
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Approved: Flo, IF, IP
Usage: Suitable for use in Flow Cytometry, Immunofluorescence, Immunoprecipitation, Effect on Heregulin (NDF) Binding (Non-inhibitory) and Effect on Tumor Growth (Non-inhibitory). Not suitable for Western Blot. Immunoprecipitation: 2 μg/mg protein lysate. Use Protein A. Well suited for Immunoprecipitation of unoccupied as well as occupied receptor. Positive control: T47D cells. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.
Not recommended for: IHC-P, WB - Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.4.
- Preservative
- Azide free
- Storage
- 4 °C,-20 °C
- Storage Comment
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Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.
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- Target
- ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))
- Alternative Name
- HER3 / ERBB3 (ERBB3 Products)
- Synonyms
- ErbB-3 antibody, HER3 antibody, LCCS2 antibody, MDA-BF-1 antibody, c-erbB-3 antibody, c-erbB3 antibody, erbB3-S antibody, p180-ErbB3 antibody, p45-sErbB3 antibody, p85-sErbB3 antibody, ERBB3 antibody, C76256 antibody, Erbb-3 antibody, Erbb3r antibody, Her3 antibody, nuc-ErbB3 antibody, erb-b2 receptor tyrosine kinase 3 antibody, v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) antibody, ERBB3 antibody, Erbb3 antibody
- Background
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Name/Gene ID: ERBB3
Subfamily: EGF Receptor
Family: Protein Kinase
Synonyms: ERBB3, C-erbB-3, C-erbB3, ErbB-3, HER3, p85-sErbB3, p45-sErbB3, MDA-BF-1, ErbB3-S, LCCS2, p180-ErbB3 - Gene ID
- 2065
- UniProt
- P21860
- Pathways
- RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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