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SNCA antibody
SNCA
Reactivity: Human, Rat, Mouse
ELISA, IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-SNCA Antibody
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Target
See all SNCA Antibodies
SNCA
(Synuclein, alpha (SNCA))
Reactivity
All reactivities for SNCA antibodies
Human, Rat, Mouse
Host
All hosts for SNCA antibodies
Rabbit
Clonality
All clonalities for SNCA antibodies
Polyclonal
Conjugate
All conjugates for SNCA antibodies
This SNCA antibody is un-conjugated
Application
All applications for SNCA antibodies
ELISA, Immunohistochemistry (IHC)
Purification
Affinity purification
Immunogen
Synthetic peptide of human SNCA
Isotype
IgG
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Discover our top product SNCA Primary Antibody
Alternatives
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Application Details
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Application Notes
IHC 1:50-1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.4 mg/mL
Buffer
PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
Preservative
Sodium azide
Handling Advice
Avoid freeze / thaw cycles.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for SNCA
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Target
SNCA
(Synuclein, alpha (SNCA))
Alternative Name
SNCA (SNCA Products )
Synonyms
snca antibody, MGC64356 antibody, LOC619283 antibody, NACP antibody, alphaSYN antibody, PARK1 antibody, PARK4 antibody, PD1 antibody, synuclein alpha L homeolog antibody, alpha-synuclein antibody, synuclein alpha antibody, synuclein, alpha antibody, snca.L antibody, LOC619283 antibody, SNCA antibody, Snca antibody
Background
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene.
NCBI Accession
NP_000336
Pathways
Synaptic Membrane , Regulation of G-Protein Coupled Receptor Protein Signaling , Positive Regulation of Endopeptidase Activity , Regulation of Carbohydrate Metabolic Process , Platelet-derived growth Factor Receptor Signaling , Negative Regulation of Transporter Activity , Regulation of long-term Neuronal Synaptic Plasticity
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