TP53I3 antibody
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- Target See all TP53I3 Antibodies
- TP53I3 (Tumor Protein P53 Inducible Protein 3 (TP53I3))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This TP53I3 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- Homo sapiens tumor protein p53 inducible protein 3 (TP53I3), transcript variant 2
- Purification
- Purified from mouse ascites fluids by affinity chromatography
- Immunogen
- Full length human recombinant protein of human TP53I3(NP_671713) produced in HEK293T cell.
- Clone
- 3B11
- Isotype
- IgG1
- Top Product
- Discover our top product TP53I3 Primary Antibody
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- Application Notes
- WB 1:2000, IHC 1:150,
- Comment
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The concentration of the product may vary between diferrent lots.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5-1.0 mg/mL
- Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
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- Target
- TP53I3 (Tumor Protein P53 Inducible Protein 3 (TP53I3))
- Alternative Name
- TP53I3 (TP53I3 Products)
- Synonyms
- MGC82892 antibody, MGC146409 antibody, PIG3 antibody, tumor protein p53 inducible protein 3 antibody, tumor protein p53 inducible protein 3 S homeolog antibody, Tp53I3 antibody, quinone oxidoreductase PIG3 antibody, TP53I3 antibody, tp53i3.S antibody, tp53i3 antibody, tp53I3 antibody
- Background
- The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. At least two transcript variants encoding the same protein have been found for this gene.
- Molecular Weight
- 35.4 kDa
- Gene ID
- 9540
- NCBI Accession
- NM_147184
- HGNC
- 9540
- Pathways
- p53 Signaling
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