FOXN1 antibody

Catalog No. ABIN2460157

Product Details anti-FOXN1 Antibody

Target: FOXN1 (Forkhead Box N1 (FOXN1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXN1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FOXN1.

Application Details

Application Notes: FOXN1 antibody can be used for detection of FOXN1 by ELISA at 1:1562500. FOXN1 antibody can be used for detection of FOXN1 by western blot at 5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store FOXN1 antibody at -20 °C.

Target Details for FOXN1

Target: FOXN1 (Forkhead Box N1 (FOXN1))

Alternative Name: FOXN1 (FOXN1 Products)

Synonyms: nude antibody, whnb antibody, FOXN1 antibody, foxN1 antibody, foxN antibody, foxn1 antibody, FKHL20 antibody, RONU antibody, WHN antibody, D11Bhm185e antibody, Fkh19 antibody, HFH-11 antibody, Hfh11 antibody, Whn antibody, nu antibody, Rnu antibody, forkhead box N1 antibody, forkhead box protein N1 antibody, FOXN1 antibody, foxn1 antibody, foxN1 antibody, LOC100125524 antibody, Foxn1 antibody

Background: Mutations in the winged-helix transcription factor gene at the nude locus in mice and rats produce the pleiotropic phenotype of hairlessness and athymia, resulting in a severely compromised immune system. This gene is orthologous to the mouse and rat genes and encodes a similar DNA-binding transcription factor that is thought to regulate keratin gene expression. A mutation in this gene has been correlated with T-cell immunodeficiency, the skin disorder congenital alopecia, and nail dystrophy. Alternative splicing in the 5' UTR of this gene has been observed.

Molecular Weight: 69 kDa

Gene ID: 8456

NCBI Accession: NP_003584

UniProt: O15353