KCNAB3 antibody

Catalog No. ABIN2461107

Product Details anti-KCNAB3 Antibody

Target: KCNAB3 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, beta Member 3 (KCNAB3))

Reactivity: Human, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNAB3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KCNAB3.

Application Details

Application Notes: KCNAB3 antibody can be used for detection of KCNAB3 by ELISA at 1:12500. KCNAB3 antibody can be used for detection of KCNAB3 by western blot at 0.65 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store KCNAB3 antibody at -20 °C.

Target Details for KCNAB3

Target: KCNAB3 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, beta Member 3 (KCNAB3))

Alternative Name: KCNAB3 (KCNAB3 Products)

Synonyms: KCNAB3 antibody, AKR6A9 antibody, KCNA3.1B antibody, KCNA3B antibody, KV-BETA-3 antibody, C330022D06Rik antibody, Kcnab4 antibody, mKv(beta)4 antibody, akr6a9 antibody, kcna3.1b antibody, kcna3b antibody, kcnb4-A antibody, kv-beta-3 antibody, kvb-b antibody, kvb4 antibody, xKvbeta4 antibody, potassium voltage-gated channel subfamily A regulatory beta subunit 3 antibody, potassium voltage-gated channel, shaker-related subfamily, beta member 3 antibody, potassium channel, voltage gated subfamily A regulatory beta subunit 3 L homeolog antibody, KCNAB3 antibody, Kcnab3 antibody, kcnab3.L antibody

Background: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog (s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits. This member and the KCNA5 gene product assemble into a heteromultimeric A-type channel that inactivates completely and is significantly faster than other A-type Kv channels.

Molecular Weight: 44 kDa

Gene ID: 9196

NCBI Accession: NP_004723

UniProt: O43448