AATF antibody

Catalog No. ABIN2461824

Product Details anti-AATF Antibody

Target: AATF (Apoptosis Antagonizing Transcription Factor (AATF))

Reactivity: Human, Mouse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AATF antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human AATF.

Application Details

Application Notes: AATF antibody can be used for detection of AATF by ELISA at 1:312500. AATF antibody can be used for detection of AATF by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store AATF antibody at -20 °C.

Target Details for AATF

Target: AATF (Apoptosis Antagonizing Transcription Factor (AATF))

Alternative Name: AATF (AATF Products)

Synonyms: AATF antibody, ded antibody, che1 antibody, che-1 antibody, cb109 antibody, sb:cb109 antibody, wu:fc13d05 antibody, zgc:162071 antibody, CHE-1 antibody, CHE1 antibody, DED antibody, 4933415H02Rik antibody, 5830465M17Rik antibody, Che-1 antibody, Trb antibody, Ded antibody, apoptosis antagonizing transcription factor antibody, Apoptosis antagonizing transcription factor antibody, apoptosis antagonizing transcription factor S homeolog antibody, AATF antibody, aatf antibody, BFR2 antibody, NAEGRDRAFT_56916 antibody, Aatf antibody, aatf.S antibody

Background: The AATF gene encodes a protein that was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis.The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis.

Molecular Weight: 63 kDa

Gene ID: 26574

NCBI Accession: NP_036270

UniProt: Q9NY61

Pathways: Neurotrophin Signaling Pathway, SARS-CoV-2 Protein Interactome