SMAD6 antibody
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- Target See all SMAD6 Antibodies
- SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SMAD6 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Purification
- Antibody is purified by peptide affinity chromatography method.
- Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SMAD6.
- Top Product
- Discover our top product SMAD6 Primary Antibody
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- Application Notes
- SMAD6 antibody can be used for detection of SMAD6 by ELISA at 1:312500. SMAD6 antibody can be used for detection of SMAD6 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Concentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Handling Advice
- As with any antibody avoid repeat freeze-thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store SMAD6 antibody at -20 °C.
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- Target
- SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))
- Alternative Name
- SMAD6 (SMAD6 Products)
- Synonyms
- madh6 antibody, madh7 antibody, Xsmad6 antibody, hst17432 antibody, AOVD2 antibody, HsT17432 antibody, MADH6 antibody, MADH7 antibody, Madh6 antibody, b2b390Clo antibody, Smad6-like antibody, smad6 antibody, wu:fb22g05 antibody, SMAD family member 6 antibody, SMAD family member 6a antibody, smad6 antibody, SMAD6 antibody, Smad6 antibody, smad6a antibody
- Background
- SMAD6 (mothers against decapentaplegic homolog 6) is an antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members, has been shown to inhibit selectively BMP (bone morphogenetic proteins) signaling by competing with the co-SMAD SMAD4 for receptor-activated SMAD1. SMAD6 is an inhibitory SMAD (I-SMAD) or antagonistic SMAD.
- Molecular Weight
- 53 kDa
- Gene ID
- 4091
- NCBI Accession
- NP_005576
- UniProt
- O43541
- Pathways
- Chromatin Binding
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