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SMAD6 antibody

SMAD6 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2463800
  • Target See all SMAD6 Antibodies
    SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))
    Reactivity
    • 52
    • 28
    • 12
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    Human
    Host
    • 54
    • 14
    Rabbit
    Clonality
    • 56
    • 12
    Polyclonal
    Conjugate
    • 41
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SMAD6 antibody is un-conjugated
    Application
    • 59
    • 39
    • 15
    • 12
    • 6
    • 3
    • 3
    • 2
    Western Blotting (WB), ELISA
    Purification
    Antibody is purified by peptide affinity chromatography method.
    Immunogen
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SMAD6.
    Top Product
    Discover our top product SMAD6 Primary Antibody
  • Application Notes
    SMAD6 antibody can be used for detection of SMAD6 by ELISA at 1:312500. SMAD6 antibody can be used for detection of SMAD6 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    Concentration
    1 mg/mL
    Buffer
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    Handling Advice
    As with any antibody avoid repeat freeze-thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store SMAD6 antibody at -20 °C.
  • Target
    SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))
    Alternative Name
    SMAD6 (SMAD6 Products)
    Synonyms
    madh6 antibody, madh7 antibody, Xsmad6 antibody, hst17432 antibody, AOVD2 antibody, HsT17432 antibody, MADH6 antibody, MADH7 antibody, Madh6 antibody, b2b390Clo antibody, Smad6-like antibody, smad6 antibody, wu:fb22g05 antibody, SMAD family member 6 antibody, SMAD family member 6a antibody, smad6 antibody, SMAD6 antibody, Smad6 antibody, smad6a antibody
    Background
    SMAD6 (mothers against decapentaplegic homolog 6) is an antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members, has been shown to inhibit selectively BMP (bone morphogenetic proteins) signaling by competing with the co-SMAD SMAD4 for receptor-activated SMAD1. SMAD6 is an inhibitory SMAD (I-SMAD) or antagonistic SMAD.
    Molecular Weight
    53 kDa
    Gene ID
    4091
    NCBI Accession
    NP_005576
    UniProt
    O43541
    Pathways
    Chromatin Binding
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