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RPS6KA1 antibody (truncated)
RPS6KA1
Reactivity: Human
WB, ELISA, IHC
Host: Mouse
Monoclonal
10B1D7A9-10B1D7E12
unconjugated
Product Details anti-RPS6KA1 Antibody
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Target
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RPS6KA1
(Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1))
Binding Specificity
All epitopes for RPS6KA1 antibodies
truncated
Reactivity
All reactivities for RPS6KA1 antibodies
Human
Host
All hosts for RPS6KA1 antibodies
Mouse
Clonality
All clonalities for RPS6KA1 antibodies
Monoclonal
Conjugate
All conjugates for RPS6KA1 antibodies
This RPS6KA1 antibody is un-conjugated
Application
All applications for RPS6KA1 antibodies
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
Immunogen
Ni-NTA purified truncated recombinant RSK1 expressed in E. Coli strain BL21 (DE3).
Clone
10B1D7A9-10B1D7E12
Isotype
IgG2a
Top Product
Discover our top product RPS6KA1 Primary Antibody
Alternatives
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Application Details
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Application Notes
Western Blot:1:500 - 1:2,000 IHC(P):1:500 - 1:2,000 ELISA:Propose dilution 1:10,000. Determining optimal working dilutions by titration test.
Restrictions
For Research Use only
Handling
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Buffer
Ascitic fluid containing 0.03 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage
-20 °C
Storage Comment
RSK1 monoclonal antibody can be stored at -20 °C, stable for one year.
Target Details for RPS6KA1
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Target
RPS6KA1
(Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1))
Alternative Name
RSK1 (RPS6KA1 Products )
Synonyms
HU-1 antibody, MAPKAPK1A antibody, RSK antibody, RSK1 antibody, Rsk1 antibody, p90rsk antibody, rsk antibody, RPS6KA antibody, hu-1 antibody, mapkapk1a antibody, rsk1 antibody, wu:fc56h07 antibody, zgc:152654 antibody, ribosomal protein S6 kinase A1 antibody, ribosomal protein S6 kinase polypeptide 1 antibody, ribosomal protein S6 kinase A1-like antibody, ribosomal protein S6 kinase A1 L homeolog antibody, ribosomal protein S6 kinase a, polypeptide 1 antibody, RPS6KA1 antibody, Rps6ka1 antibody, RPS6KA1L antibody, rps6ka1.L antibody, rps6ka1 antibody
Background
Rsk1 is a member of a family of 90 kDa ribosomal protein S6 kinases, which includes Rsk1, Rsk2 and Rsk3. These are broadly expressed serine / threonine protein kinases activated in response to mitogenic stimuli, including extracellular signal regulated protein kinases Erk1 and Erk2. Rsk1 is activated by MAPK in vitro and in vivo via phosphorylation. Active Rsks appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c-Fos and CREB. RSK proteins possess two separate kinase domains, the C terminal kinase domain and the N terminal kinase domain, separated by a linker region containing a hydrophobic motif. RSK is activated by many stimuli including growth factors, phorbol esters, cAMP, heat shock, and irradiation.
Gene ID
6195
UniProt
Q15418
Pathways
MAPK Signaling , Neurotrophin Signaling Pathway , Activation of Innate immune Response , Toll-Like Receptors Cascades
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