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TLR4 antibody

TLR4 Reactivity: Human FACS, Func Host: Mouse Monoclonal HTA125 unconjugated
Catalog No. ABIN2567453
  • Target See all TLR4 Antibodies
    TLR4 (Toll-Like Receptor 4 (TLR4))
    Reactivity
    • 178
    • 93
    • 75
    • 37
    • 23
    • 20
    • 19
    • 19
    • 5
    • 2
    • 1
    • 1
    Human
    Host
    • 134
    • 70
    • 5
    • 4
    Mouse
    Clonality
    • 138
    • 75
    Monoclonal
    Conjugate
    • 97
    • 22
    • 20
    • 14
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TLR4 antibody is un-conjugated
    Application
    • 155
    • 126
    • 56
    • 50
    • 35
    • 29
    • 27
    • 27
    • 26
    • 24
    • 13
    • 8
    • 8
    • 7
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Functional Studies (Func)
    Specificity
    The HTA125 monoclonal antibody specifically reacts with human CD284, a 110kDA type I transmembrane signaling molecule known as the Toll-like Receptor 4 (TLR4).
    Purification
    The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.
    Clone
    HTA125
    Isotype
    IgG2a kappa
    Top Product
    Discover our top product TLR4 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Phosphate-buffered aqueous solution, ph7.2.
    Storage
    4 °C
    Storage Comment
    The product should be stored undiluted at 4°C. Do not freeze.
  • Target
    TLR4 (Toll-Like Receptor 4 (TLR4))
    Alternative Name
    CD284 (TLR4 Products)
    Synonyms
    ARMD10 antibody, CD284 antibody, TLR-4 antibody, TOLL antibody, Lps antibody, Ly87 antibody, Ran/M1 antibody, Rasl2-8 antibody, toll like receptor 4 antibody, toll-like receptor 4 antibody, TLR4 antibody, Tlr4 antibody
    Background
    The HTA125 monoclonal antibody specifically reacts with human CD284, a 110kDA type I transmembrane signaling molecule known as the Toll-like Receptor 4 (TLR4). CD284 is an important molecule in the innate immunity response to bacterial lipoproteins. It is expressed by monocytes, macrophages, and endothelial cells. The HTA125 antibody can block Lipopolysaccharide-induced cytokine production and immunoprecipitate human TLR4.
    Gene ID
    7099
    UniProt
    O00206
    Pathways
    TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins
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