MKP-1/2 antibody (pSer296, pSer318)

Catalog No. ABIN2568369

Product Details anti-MKP-1/2 Antibody

Target: MKP-1/2 (DUSP1/4) (Dual Specificity Phosphatase 1/4 (DUSP1/4))

Binding Specificity: pSer296, pSer318

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MKP-1/2 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: The antibody detects endogenous level of MKP-1/2 only when phosphorylated at serine 296/318.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: MKP-1/2 (phospho Ser296/318) antibody was raised against a peptide sequence around phosphorylation site of serine 296/318 (I-I-S (p)-P-N) derived from Human MKP-1/2 .

Isotype: IgG

Application Details

Application Notes: Western Blot: 1:500~1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store antibody at -20°C for up to one year.

Target Details for MKP-1/2

Target: MKP-1/2 (DUSP1/4) (Dual Specificity Phosphatase 1/4 (DUSP1/4))

Alternative Name: MKP-1/2 (DUSP1/4 Products)

Background: Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-183' and 'Tyr-185', regulating its activity during the meiotic cell cycle.

Molecular Weight: 45 kDa

Gene ID: 1843, 1846

NCBI Accession: NP_004408, NP_001385

UniProt: P28562, Q13115