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TRKB antibody (pTyr706, pTyr707)
NTRK2
Reactivity: Human, Rat, Mouse
IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-TRKB Antibody
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Target
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TRKB (NTRK2)
(Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2))
Binding Specificity
All epitopes for TRKB antibodies
pTyr706, pTyr707
Reactivity
All reactivities for TRKB antibodies
Human, Rat, Mouse
Host
All hosts for TRKB antibodies
Rabbit
Clonality
All clonalities for TRKB antibodies
Polyclonal
Conjugate
All conjugates for TRKB antibodies
This TRKB antibody is un-conjugated
Application
All applications for TRKB antibodies
Immunohistochemistry (IHC)
Specificity
The antibody detects endogenous levels of Trk B only when phosphorylated at tyrosine 706 and tyrosine 707.
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Immunogen
Trk B (phospho Tyr706/Tyr707) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 706/tyrosine 707 (T-D-Y (p)-Y (p)-R-V)derived from Human Trk B.
Isotype
IgG
Top Product
Discover our top product NTRK2 Primary Antibody
Alternatives
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anti-Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) (AA 57-70), (Extracellular Domain) antibody
NTRK2
Reactivity: Human, Rat, Mouse
WB, IHC, IF, FACS, ICC, LCI
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store antibody at -20°C for up to one year.
Target Details for TRKB
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Target
TRKB (NTRK2)
(Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2))
Alternative Name
Trk B (NTRK2 Products )
Synonyms
trkb antibody, trkb-b antibody, xtrkb antibody, si:ch211-220b11.1 antibody, trkB2 antibody, NTRK2 antibody, ntrk2 antibody, gp145-trkb antibody, TRKB antibody, GP145-TrkB antibody, trk-B antibody, AI848316 antibody, C030027L06Rik antibody, Tkrb antibody, trkB antibody, RATTRKB1 antibody, TRKB1 antibody, Trk-B antibody, TrkB antibody, neurotrophic receptor tyrosine kinase 2 antibody, neurotrophic receptor tyrosine kinase 2 L homeolog antibody, neurotrophic tyrosine kinase, receptor, type 2b antibody, neurotrophic receptor tyrosine kinase 2 S homeolog antibody, neurotrophic tyrosine kinase, receptor, type 2 antibody, NTRK2 antibody, ntrk2.L antibody, ntrk2b antibody, ntrk2.S antibody, ntrk2 antibody, Ntrk2 antibody
Background
Receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (NGF). Involved in the development and/or maintenance of the nervous system. This is a tyrosine-protein kinase receptor. Known substrates for the TRK receptors are SHC1, PI-3 kinase, and PLC-gamma-1.
Molecular Weight
91 kDa
Gene ID
4915
NCBI Accession
NP_001018074
UniProt
Q16620
Pathways
RTK Signaling , Neurotrophin Signaling Pathway , cAMP Metabolic Process , Skeletal Muscle Fiber Development , Feeding Behaviour , Dicarboxylic Acid Transport
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