SHC1 antibody (pTyr427)
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- Target See all SHC1 Antibodies
- SHC1 (SHC (Src Homology 2 Domain Containing) Transforming Protein 1 (SHC1))
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Binding Specificity
- pTyr427
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SHC1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Specificity
- Recognizes endogenous levels of Shc1 only when phosphorylated at tyrosine 427.
- Purification
- Immunoaffinity purified
- Immunogen
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Synthesized phosphopeptide derived from human Shc1 around the phosphorylation site of tyrosine 427 (P-S-YP-V-N).
Type of Immunogen: Synthetic phospho-peptide - Isotype
- IgG
- Top Product
- Discover our top product SHC1 Primary Antibody
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- Application Notes
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Approved: IHC (1:50 - 1:100), WB (1:500 - 1:1000)
Usage: Suitable for use in Western Blot and Immunohistochemistry. Western Blot: 1:500-1:1000. Immunohistochemistry: 1:50-1:100. - Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.4, 150 mM sodium chloride, 0.02 % sodium azide, 50 % glycerol
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- Target
- SHC1 (SHC (Src Homology 2 Domain Containing) Transforming Protein 1 (SHC1))
- Alternative Name
- p66 / SHC (SHC1 Products)
- Synonyms
- SHC1 antibody, SHC antibody, SHCA antibody, P66shc antibody, si:dkey-246i14.4 antibody, wu:fc10h03 antibody, shc antibody, p66shc antibody, Shc antibody, ShcA antibody, p66 antibody, SHC adaptor protein 1 antibody, Shc1p antibody, squalene--hopene cyclase antibody, SHC (Src homology 2 domain containing) transforming protein 1 antibody, SHC (Src homology 2 domain containing) transforming protein 1 L homeolog antibody, src homology 2 domain-containing transforming protein C1 antibody, SHC1 antibody, shc1 antibody, Shc1 antibody, shc1.L antibody
- Background
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Name/Gene ID: SHC1
Synonyms: SHC1, p46 shc, p52 shc, SH2 domain protein C1, p66, SHCA, SHC, SHC-transforming protein 1, SHC-transforming protein 3, SHC-transforming protein A - Gene ID
- 6464
- UniProt
- P29353
- Pathways
- RTK Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, ER-Nucleus Signaling, Signaling Events mediated by VEGFR1 and VEGFR2
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