Endoglin antibody
-
- Target See all Endoglin (ENG) Antibodies
- Endoglin (ENG)
-
Reactivity
- Human
-
Host
- Mouse
-
Clonality
- Monoclonal
-
Conjugate
- This Endoglin antibody is un-conjugated
-
Application
- Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Zinc-fixed Sections) (IHC (zinc))
- Brand
- BD Pharmingen™
- Characteristics
-
The 266 monoclonal antibody specifically binds to CD105. CD105 presents an integral membrane homodimer protein with subunits of 95 kDa found on vascular endothelial cells and syncytiotrophoblasts of placenta. CD105 is weakly expressed on stromal fibroblasts. It is also expressed on U937 cells, activated macrophages, and mesenchymal stem cells. CD105 is a component of the TGF-β receptor system in human umbilical vein endothelial cells and binds TGF-β1 and TGF-β3 with high affinity but does not bind toTGF-β2. Expression of CD105 is increased on activated endothelium in tissues undergoing angiogenesis, such as in tumors, or in cases of wound healing or dermal inflammation.
BD Pharmingen™ Purified Mouse Anti-Human CD105 - Purified - Clone 266 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg - Purification
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- Immunogen
- Human Umbilical Vein Endothelial Cells
- Clone
- 266
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product ENG Primary Antibody
-
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Concentration
- 0.5 mg/mL
- Buffer
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Store undiluted at 4°C.
-
-
Regulated expression on human macrophages of endoglin, an Arg-Gly-Asp-containing surface antigen." in: European journal of immunology, Vol. 22, Issue 2, pp. 393-7, (1992) (PubMed).
: "
-
Regulated expression on human macrophages of endoglin, an Arg-Gly-Asp-containing surface antigen." in: European journal of immunology, Vol. 22, Issue 2, pp. 393-7, (1992) (PubMed).
-
- Target
- Endoglin (ENG)
- Alternative Name
- CD105 (ENG Products)
- Synonyms
- ENG antibody, MGC137842 antibody, DKFZp469D0419 antibody, END antibody, HHT1 antibody, ORW1 antibody, AI528660 antibody, AI662476 antibody, CD105 antibody, S-endoglin antibody, endoglin antibody, ENG antibody, Eng antibody
- Background
- Synonyms: Endoglin, ENG, END, HHT1, ORW, ORW1
-