GNS antibody (C-Term)
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- Target See all GNS Antibodies
- GNS (Glucosamine (N-Acetyl)-6-Sulfatase (GNS))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Cow, Goat, Guinea Pig, Horse, Rabbit, Dog, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GNS antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- YIFYTSDNGY HTGQFSLPID KRQLYEFDIK VPLLVRGPGI KPNQTSKMLV
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
- Characteristics
- This is a rabbit polyclonal antibody against Gns. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide corresponding to a region of Rat
- Top Product
- Discover our top product GNS Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 519 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- GNS (Glucosamine (N-Acetyl)-6-Sulfatase (GNS))
- Alternative Name
- Gns (GNS Products)
- Synonyms
- G6S antibody, 2610016K11Rik antibody, AU042285 antibody, C87209 antibody, N28088 antibody, NV14559 antibody, N-acetylglucosamine-6-sulfatase antibody, zgc:114066 antibody, gns antibody, wu:fi20h10 antibody, zgc:55370 antibody, glucosamine (N-acetyl)-6-sulfatase antibody, glucosamine (N-acetyl)-6-sulfatase S homeolog antibody, glucosamine (N-acetyl)-6-sulfatase a antibody, N-acetylglucosamine-6-sulfatase antibody, glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID), b antibody, GNS antibody, Gns antibody, gns.S antibody, gns antibody, gnsa antibody, CpipJ_CPIJ000745 antibody, Sros_7372 antibody, VDBG_04409 antibody, Halhy_3165 antibody, gnsb antibody
- Background
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GNS is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparin sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder ucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome.
Alias Symbols: Gns
Protein Size: 519 - Molecular Weight
- 58 kDa
- Gene ID
- 299825
- NCBI Accession
- NM_001011989, NP_001011989
- UniProt
- Q5M918
- Pathways
- Glycosaminoglycan Metabolic Process
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