XRCC3 antibody (Middle Region)
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- Target See all XRCC3 Antibodies
- XRCC3 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Dog, Cow, Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This XRCC3 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- LAVQFPRQHG GLEAGAVYIC TEDAFPHKRL QQLMAQQPRL RTDVPGELLQ
- Predicted Reactivity
- Cow: 83%, Dog: 92%, Guinea Pig: 92%, Human: 100%, Mouse: 79%
- Characteristics
- This is a rabbit polyclonal antibody against XRCC3. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product XRCC3 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 346 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- XRCC3 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3))
- Alternative Name
- XRCC3 (XRCC3 Products)
- Synonyms
- CMM6 antibody, 4432412E01Rik antibody, AI182522 antibody, AW537713 antibody, MGC69118 antibody, im:7142103 antibody, zgc:101608 antibody, si:dkey-11b8.1 antibody, xrcc3 antibody, XRCC3 antibody, X-ray repair cross complementing 3 antibody, X-ray repair complementing defective repair in Chinese hamster cells 3 antibody, X-ray repair complementing defective repair in Chinese hamster cells 3 L homeolog antibody, XRCC3 antibody, Xrcc3 antibody, xrcc3.L antibody, xrcc3 antibody
- Background
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This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
Alias Symbols: CMM6
Protein Interaction Partner: SWSAP1, ZSWIM7, UBC, FANCG, BRCA2, ZNHIT3, RAD51D, RAD51C, RAD51,
Protein Size: 346 - Molecular Weight
- 38 kDa
- Gene ID
- 7517
- NCBI Accession
- NM_005432, NP_005423
- UniProt
- O43542
- Pathways
- DNA Damage Repair
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