SPI1 antibody (Middle Region)
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- Target See all SPI1 Antibodies
- SPI1 (Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SPI1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- HPSLGHQVSY LPRMCLQYPS LSPAQPSSDE EEGERQSPPL EVSDGEADGL
- Predicted Reactivity
- Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 92%, Pig: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against SPI1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human SPI1
- Top Product
- Discover our top product SPI1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 264 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- SPI1 (Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1))
- Alternative Name
- SPI1 (SPI1 Products)
- Synonyms
- OF antibody, PU.1 antibody, SFPI1 antibody, SPI-1 antibody, SPI-A antibody, Dis-1 antibody, Dis1 antibody, Sfpi-1 antibody, Sfpi1 antibody, Spi-1 antibody, Tcfpu1 antibody, Tfpu.1 antibody, Pu.1 antibody, cb1086 antibody, pu.1 antibody, pu1 antibody, sfpi1 antibody, si:by184l24.2 antibody, spi1 antibody, SPI1/PU.1 antibody, spi1l antibody, zgc:152991 antibody, Spi-1 proto-oncogene antibody, spleen focus forming virus (SFFV) proviral integration oncogene antibody, Spi-1 proto-oncogene b antibody, Spi-1 proto-oncogene a antibody, SPI1 antibody, Spi1 antibody, spi1b antibody, spi1a antibody
- Background
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SPI1 is known to collaborate with multiple transcription factors and to regulate expression of immunoglobulin genes. Lack of SPI1 expression is associated with defective immunoglobulin transcription in Hodgkin and Reed-Sternberg cells of classical Hodgkin disease
Alias Symbols: OF, PU.1, SFPI1, SPI-1, SPI-A
Protein Interaction Partner: HOXA10, TMX1, VAV1, IRF1, IRF8, GATA3, GATA2, GATA1, GFI1, TBP, RB1, BYRF1, RARA, PML, HDAC3, SKI, SIN3A, HDAC1, BCL6, CEBPA, PIP, SPIB, SSRP1, IRF4, KAT6A, CEBPE, NFATC1, CREBBP, NONO, CEBPB, JUN, ERG, NFKB1, MITF, FUS, CREM, ATF1, CEBPD, MECP2, DNMT3B,
Protein Size: 264 - Molecular Weight
- 30 kDa
- Gene ID
- 6688
- NCBI Accession
- NM_003120, NP_003111
- UniProt
- P17947
- Pathways
- Stem Cell Maintenance
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