c-Rel antibody (C-Term)

Catalog No. ABIN2779888

Product Details anti-c-Rel Antibody

Target: c-Rel (REL proto-oncogene (c-Rel))

Binding Specificity: C-Term

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This c-Rel antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: FSCVDNGLMN EPGLSDDANN PTFVQSSHYS VNTLQSEQLS DPFTYGFFKI

Predicted Reactivity: Mouse: 100%

Characteristics: This is a rabbit polyclonal antibody against Rel. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of mouse REL

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for c-Rel

Target: c-Rel (REL proto-oncogene (c-Rel))

Alternative Name: Rel (c-Rel Products)

Synonyms: C-Rel antibody, c-Rel antibody, NFkB antibody, c-rel antibody, zgc:100833 antibody, Xrel2 antibody, Xrel3 antibody, rel antibody, rel-A antibody, rel2 antibody, rel3 antibody, v-rel antibody, xrel antibody, REL proto-oncogene, NF-kB subunit antibody, reticuloendotheliosis oncogene antibody, RELA proto-oncogene, NF-kB subunit antibody, v-rel avian reticuloendotheliosis viral oncogene homolog antibody, v-rel avian reticuloendotheliosis viral oncogene homolog L homeolog antibody, ribonuclease A family member 2 pseudogene antibody, REL antibody, Rel antibody, Rela antibody, rel antibody, rel.L antibody, ECRP antibody

Background: This gene encodes a protein that belongs to the Rel homology domain/immunoglobulin-like fold, plexin, transcription factor (RHD/IPT) family. Members of this family regulate genes involved in apoptosis, inflammation, the immune response, and oncogenic processes. This proto-oncogene plays a role in the survival and proliferation of B lymphocytes. Mutation or amplification of this gene is associated with B-cell lymphomas, including Hodgkin's lymphoma. Single nucleotide polymorphisms in this gene are associated with susceptibility to ulcerative colitis and rheumatoid arthritis. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: C-Rel
Protein Size: 587

Molecular Weight: 64 kDa

Gene ID: 5966

NCBI Accession: NM_001291746, NP_001278675

UniProt: Q04864