Tumor Protein p73 antibody (N-Term)

Catalog No. ABIN2780309

Product Details anti-Tumor Protein p73 Antibody

Target: Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tumor Protein p73 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SNMDVFHLQG MAQFNLLSSA MDQMGSRAAP ASPYTPEHAA SAPTHSPYAQ

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Human: 93%, Mouse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against Trp73. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 631 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Tumor Protein p73

Target: Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

Alternative Name: Trp73 (TP73 Products)

Synonyms: P73 antibody, Trp73 antibody, TP73 antibody, tp73 antibody, Tp73 antibody, p73 antibody, TAp73 antibody, zp73theta antibody, tumor protein p73 antibody, transformation related protein 73 antibody, TP73 antibody, Tp73 antibody, tp73 antibody, Trp73 antibody

Background: Trp73 participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. Trp73 may be a tumor suppressor protein.
Alias Symbols: p73, Tp73
Protein Interaction Partner: Mapk8, Trp53, Med16, Trp73, Trp63,
Protein Size: 631

Molecular Weight: 69 kDa

Gene ID: 22062

NCBI Accession: NM_011642, NP_035772

UniProt: Q9JJP2

Pathways: Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus