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ERCC6 antibody (C-Term)
ERCC6
Reactivity: Human, Rat, Mouse, Cow, Rabbit, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio)
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-ERCC6 Antibody
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Target
See all ERCC6 Antibodies
ERCC6
(Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6 (ERCC6))
Binding Specificity
All epitopes for ERCC6 antibodies
C-Term
Reactivity
Human, Rat, Mouse, Cow, Rabbit, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio)
Host
All hosts for ERCC6 antibodies
Rabbit
Clonality
All clonalities for ERCC6 antibodies
Polyclonal
Conjugate
All conjugates for ERCC6 antibodies
This ERCC6 antibody is un-conjugated
Application
All applications for ERCC6 antibodies
Western Blotting (WB)
Sequence
EASALLPTTE HDDLLVEMRN FIAFQAHTDG QASTREILQE FESKLSASQS
Predicted Reactivity
Cow: 86%, Dog: 79%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 79%, Rat: 86%, Zebrafish: 79%
Characteristics
This is a rabbit polyclonal antibody against ERCC6. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of human ERCC6
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Application Details
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Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeat freeze-thaw cycles.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for ERCC6
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Target
ERCC6
(Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6 (ERCC6))
Alternative Name
ERCC6 (ERCC6 Products )
Synonyms
ARMD5 antibody, CKN2 antibody, COFS antibody, COFS1 antibody, CSB antibody, RAD26 antibody, UVSS1 antibody, 4732403I04 antibody, C130058G22Rik antibody, ercc6 antibody, Ercc6 antibody, ERCC excision repair 6, chromatin remodeling factor antibody, excision repair cross-complementing rodent repair deficiency, complementation group 6 antibody, excision repair cross-complementation group 6 antibody, DNA excision repair protein ERCC-6 antibody, ERCC6 antibody, Ercc6 antibody, ercc6 antibody, LOC100719487 antibody
Background
This gene encodes a DNA-binding protein that is important in transcription-coupled excision repair. The encoded protein has ATP-stimulated ATPase activity, interacts with several transcription and excision repair proteins, and may promote complex formation at DNA repair sites. Mutations in this gene are associated with Cockayne syndrome type B and cerebrooculofacioskeletal syndrome 1. Naturally-occurring readthrough transcription occurs between this gene and the adjacent PGBD3 gene (GeneID:267004), and results in a fusion protein that shares sequence with the product of each individual gene. The readthrough locus is represented by GeneID:101243544. Alias Symbols: CSB, CKN2, COFS, ARMD5, COFS1, RAD26, UVSS1 Protein Size: 863
Molecular Weight
94 kDa
Gene ID
2074
NCBI Accession
NM_000124 , NP_000115
UniProt
Q03468
Pathways
DNA Damage Repair , Chromatin Binding
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