SLC7A8 antibody (Middle Region)

Catalog No. ABIN2781629

Product Details anti-SLC7A8 Antibody

Target: SLC7A8 (Solute Carrier Family 7 (Amino Acid Transporter, L-Type), Member 8 (SLC7A8))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Zebrafish (Danio rerio), Horse, Rabbit, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC7A8 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PRAIFISIPL VTFVYVFANV AYVTAMSPQE LLASNAVAVT FGEKLLGVMA

Specificity: 100 % homologous to isoforms 1 (58 kDa), 2 (37 kDa), 3 (35 kDa) and 4 (48 kDa).

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against SLC7A8. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SLC7A8

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 332 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-SLC7A8 antibody (ABIN2781629)

Romanet, Aschenbach, Pieper, Zentek, Htoo, Whelan, Mastrototaro: "Expression of proposed methionine transporters along the gastrointestinal tract of pigs and their regulation by dietary methionine sources." in: Genes & nutrition, Vol. 16, Issue 1, pp. 14, (2021) (PubMed).

Target Details for SLC7A8

Target: SLC7A8 (Solute Carrier Family 7 (Amino Acid Transporter, L-Type), Member 8 (SLC7A8))

Alternative Name: SLC7A8 (SLC7A8 Products)

Synonyms: LAT2 antibody, LPI-PC1 antibody, Lat2 antibody, Lat4 antibody, XAA2 antibody, lat2 antibody, lpi-pc1 antibody, 4F2LC-5 antibody, AA408822 antibody, si:ch211-14a17.3 antibody, si:zc14a17.3 antibody, slc7a8 antibody, solute carrier family 7 member 8 antibody, solute carrier family 7 member 8 L homeolog antibody, solute carrier family 7 (amino acid transporter, L-type), member 8 antibody, solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 antibody, solute carrier family 7 (amino acid transporter light chain, L system), member 8b antibody, SLC7A8 antibody, Slc7a8 antibody, slc7a8.L antibody, slc7a8 antibody, slc7a8b antibody

Background: SLC7A8 is sodium-independent, high-affinity transport of large neutral amino acids. It has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine. L-alanine is transported at physiological concentrations. SLC7A8 also plays a role in basolateral (re)absorption of neutral amino acids.
Alias Symbols: LAT2, LPI-PC1
Protein Interaction Partner: SLC3A1, UBC, SLC3A2,
Protein Size: 332

Molecular Weight: 37 kDa

Gene ID: 23428

NCBI Accession: NM_182728, NP_877392