SERPINB8 antibody (Middle Region)
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- Target See all SERPINB8 Antibodies
- SERPINB8 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 8 (SERPINB8))
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Binding Specificity
- Middle Region
- Reactivity
- Human, Mouse, Rat, Rabbit, Dog, Horse, Cow, Pig, Guinea Pig, Sheep
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SERPINB8 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- KAWTNSEKLT KSKVQVFLPR LKLEESYDLE PFLRRLGMID AFDEAKADFS
- Predicted Reactivity
- Cow: 91%, Dog: 92%, Guinea Pig: 83%, Horse: 92%, Human: 100%, Mouse: 100%, Pig: 92%, Rabbit: 86%, Rat: 100%, Sheep: 91%
- Characteristics
- This is a rabbit polyclonal antibody against SERPINB8. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human SERPINB8
- Top Product
- Discover our top product SERPINB8 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 374 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- SERPINB8 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 8 (SERPINB8))
- Alternative Name
- SERPINB8 (SERPINB8 Products)
- Synonyms
- pi8 antibody, cap2 antibody, CAP-2 antibody, CAP2 antibody, NK10 antibody, Spi8 antibody, ovalbumin antibody, PI8 antibody, serpin family B member 8 antibody, serpin B8 antibody, serpin peptidase inhibitor, clade B (ovalbumin), member 8 antibody, serine (or cysteine) peptidase inhibitor, clade B, member 8 antibody, Serpinb8 antibody, SERPINB8 antibody, LOC607205 antibody, serpinb8 antibody, LOC100424017 antibody
- Background
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The superfamily of high molecular weight serine proteinase inhibitors (serpins) regulate a diverse set of intracellular and extracellular processes such as complement activation, fibrinolysis, coagulation, cellular differentiation, tumor suppression, apoptosis, and cell migration. Serpins are characterized by well-conserved a tertiary structure that consists of 3 beta sheets and 8 or 9 alpha helices (Huber and Carrell, 1989 [PubMed 2690952]). A critical portion of the molecule, the reactive center loop connects beta sheets A and C. Protease inhibitor-8 (PI8, SERPINB8) is a member of the ov-serpin subfamily, which, relative to the archetypal serpin PI1 (MIM 107400), is characterized by a high degree of homology to chicken ovalbumin, lack of N- and C-terminal extensions, absence of a signal peptide, and a serine rather than an asparagine residue at the penultimate position (summary by Bartuski et al., 1997 [PubMed 9268635]).
Alias Symbols: CAP2, PI8
Protein Interaction Partner: SUMO2, LARS, UBC, CAP1, PRSS1, F10, F2, FURIN, BCL2,
Protein Size: 374 - Molecular Weight
- 43 kDa
- Gene ID
- 5271
- NCBI Accession
- NM_198833, NP_942130
- UniProt
- P50452
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